neobookRx

Psoriasis

Standard Treatment Guidelines and Essential Medicines List for South Africa, Hospital Level, Adults 2019 Edition

Description

General measures

Medicine treatment

Referral


L40.0-5/L40.8-9

DESCRIPTION

  • This is an inflammatory condition of the skin and joints of unknown aetiology. 
  • Scaly red, papules and plaques over extensor surfaces and on the scalp are common. 
  • The nails and skin folds are often involved. 
  • In exceptional cases, it is localised to palms and soles and pustular skin lesions are seen, especially following rapid treatment withdrawal, e.g. steroids or systemic agents.

GENERAL MEASURES

  • Counselling regarding precipitating factors and chronicity.
  • Encourage sun exposure as tolerated.

MEDICINE TREATMENT

Local plaques

Maintenance therapy

  • Coal tar 5%, topical, apply at night
    • Avoid use on the face, flexures, and genitalia

For flares

  • Potent topical corticosteroids, e.g.:
    • Betamethasone 0.1%, topical, apply 12 hourly
    • Decrease according to severity, reduce to hydrocortisone 1%, cream, then stop

LoE:IVbxii

Scalp psoriasis

Maintenance therapy

  • Wash with coal tar containing shampoo

OR

  • Coal tar 1%, topical, apply at night, under occlusion, and wash out the next morning

For flares

  • Potent topical corticosteroids, e.g.:
    • Betamethasone 0.1% lotion, topical, apply once daily

LoE:IVbxiii


Note

- Avoid systemic corticosteroids.
- Patient adherence is the greatest barrier to treatment success with topical therapies.


REFERRAL

  • Inadequate response to topical treatment.
  • Severe disease, especially if joint involvement.

Click here to access the pdf.


Standard Treatment Guidelines and Essential Medicines List for South Africa, Adult Hospital Level, 2020-2024_Version 1.0_07 November 2024

Chapter 4 Dermatology_4.8 Psoriasis

Drugs mentioned

ICD-10 codes

NeoHealth® ID 19860 · updated 7/8/2025