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Recurrent UTI

Standard Treatment Guidelines and Essential Medicines List for South Africa, Hospital Level, Adults 2019 Edition

Description

General measures

Medicine treatment

Referral/consultation


N10.0/N30.9/N39.0

DESCRIPTION

Recurrences of uncomplicated and/or complicated UTIs, with a frequency of at least three UTIs/year or two UTIs in the last six months. Send urine for microscopy, culture and sensitivity as treatment is determined by the results.

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GENERAL MEASURES

Women should void soon after intercourse.
Identify and treat hormone-deficient atrophic vulvo-vaginitis in the elderly.

MEDICINE TREATMENT

Prophylaxis Z29.9

To reduce risk of recurrence in patients with >3 infections/year requires continuous prophylaxis for 6 months:

  • Cotrimoxazole 80/400 mg, oral, 1 tablet at night.

Treatment

Treat according to microscopy, culture and sensitivity.

REFERRAL/CONSULTATION

  • Failure to respond to prophylactic treatment.
  • Uncertain diagnosis.
  • Recurrent infections where no facilities exist for adequate culture of urine.
  • All complicated recurrent UTIs.
  • STI pathogens.

Click here to access the pdf.


Standard Treatment Guidelines and Essential Medicines List for South Africa, Adult Hospital Level, 2020-2024_Version 1.0_17 October 2024

Chapter 7 Nephrology/Urological Disorders_7.3 Urological Disorders_7.3.3 Recurrent UTI

ICD-10 codes

NeoHealth® ID 17820 · updated 7/9/2025