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References - Acute Pain
Amin FM, Asghar MS, Hougaard A, et al. Magnetic resonance angiography of intracranial and extracranial arteries in patients with spontaneous migraine without aura: a cross-sectional study. Lancet Neurol. 2013;12(5):454-61. https://doi.org/10.1016/ S1474-4422(13)70067-X. Amrein R, Hetzel W, Bonetti EP, Gerecke M. Clinical pharmacology of dormicum (midazolam) and anexate (flumazenil). Resuscitation
- Amin FM, Asghar MS, Hougaard A, et al. Magnetic resonance angiography of intracranial and extracranial arteries in patients with spontaneous migraine without aura: a cross-sectional study. Lancet Neurol. 2013;12(5):454-61. https://doi.org/10.1016/ S1474-4422(13)70067-X.
- Amrein R, Hetzel W, Bonetti EP, Gerecke M. Clinical pharmacology of dormicum (midazolam) and anexate (flumazenil). Resuscitation. 1988;16 Suppl:S5-S27. https://doi.org/10.1016/0300-9572(88)90002-0.
- Attal N, Rouaud J, Brasseur L, Chauvin M, Bouhassira D. Systemic lidocaine in pain due to peripheral nerve injury and predictors of response. Neurology. 2004;62:218-25. https://doi.org/10.1212/01.WNL.0000103237.62009.77.
- Aubrun F, Langeron O, Quesnel C, Coriat P, Riou B. Relationships between measurement of pain using visual analog score and morphine requirements during postoperative intravenous morphine titration. Anesthesiology. 2003;98(6):1415-21. https://doi. org/10.1097/00000542-200306000-00017.
- Aubrun F, Mazoit JX, Riou B. Postoperative intravenous morphine titration. Br J Anaesth. 2012;108(2):193-201. https://doi.org/10.1093/bja/ aer458.
- Aubrun F, Monsel S, Langeron O, Coriat P, Riou B. Postoperative titration of intravenous morphine in the elderly patient. Anesthesiology. 2002;96(1):17-23. https://doi.org/10.1097/00000542-200201000-00009.
- Baidya DK, Agarwal A, Khanna P, Arora MK. Pregabalin in acute and chronic pain. J Anaesthesiol Clin Pharmacol. 2011;27(3):307-14. https://doi.org/10.4103/0970-9185.83672.
- Barmherzig R, Kingston W. Occipital neuralgia and cervicogenic headache: diagnosis and management. Curr Neurol Neurosci Rep. 2019;19(5):20. https://doi.org/10.1007/s11910-019-0937-8.
- Bates D, Schultheis BC, Hanes MC, et al. A comprehensive algorithm for management of neuropathic pain. Pain Med. 2019;20(Suppl 1):S2-S12. https://doi.org/10.1093/pm/pnz075.
- Battershill AJ, Keating GM. Spotlight on remifentanil: its analgesic and sedative use in the intensive care unit. CNS Drugs. 2006;20(6):519- 22. https://doi.org/10.2165/00023210-200620060-00006.
- Bayuo J, Munn Z, Campbell J. Assessment and management of burn pain at the Komfo Anokye Teaching Hospital: a best practice implementation project. JBI Database Syst Rev Implement Rep. 2017;15(9):2398-418. https://doi.org/10.11124/JBISRIR-2016-003272.
- Becker WJ. Acute migraine treatment. Continuum. 2015;21(4 Headache):953-72. https://doi.org/10.1212/CON.0000000000000192.
- Bentley ML, Corwin HL, Dasta J. Drug-induced acute kidney injury in the critically ill adult: recognition and prevention strategies. Crit Care Med. 2010;38(6 Suppl):S169-74. https://doi.org/10.1097/CCM.0b013e3181de0c60.
- Birbeck GL, French JA, Perucca E, et al. Quality standards subcommittee of the American Academy of Neurology, ad hoc task force of The Commission on Therapeutic Strategies of The International League Against Epilepsy. Antiepileptic drug selection for people with HIV/ AIDS: evidence-based guidelines from the ILAE and AAN. Epilepsia. 2012;53(1):207-14. https://doi.org/10.1111/j.1528-1167.2011.03335.x.
- Bisgaard T, Warltier DC. Analgesic treatment after laparoscopic cholecystectomy: a critical assessment of the evidence. Anesthesiology. 2006;104(4):835-46. https://doi.org/10.1097/00000542-200604000-00030.
- Boland EG, Mulvey MR, Bennett MI. Classification of neuropathic pain in cancer patients. Curr Opin Support Palliat Care. 2015;9(2):112-5. https://doi.org/10.1097/SPC.0000000000000136.
- Boyter E. Idiopathic intracranial hypertension. JAAPA. 2019;32(5):30-5. https://doi.org/10.1097/01.JAA.0000554732.85914.91.
- Bril V, England J, Franklin GM, et al. Evidence-based guideline: treatment of painful diabetic neuropathy: report of the American Academy of Neurology, the American Association of Neuromuscular and Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation. PM R. 2011;3(4):345-52, 352.e1-21. https://doi.org/10.1212/WNL.0b013e3182166ebe.
- Butler KC, Selden B, Pollack CV Jr. Relief by naloxone of morphine-induced spasm of the sphincter of Oddi in a post-cholecystectomy patient. J Emerg Med. 2001;21(2):129-31. https://doi.org/10.1016/S0736-4679(01)00355-9.
- Cáceres-Jereza LE, Gomezese-Riberob OF, Reyes-Cárdenasc LI, et al. Management of acute pain in extensive burn injury: Nonsystematic review of the literature. Rev Colomb Anestesiol. 2018;46(1):49-54. https://doi.org/10.1097/CJ9.0000000000000009.
- Capone ML, Tacconelli S, Di Francesco L, et al. Pharmacodynamic of cyclooxygenase inhibitors in humans. Prostaglandins Other Lipid Mediat. 2007;82(1-4):85-94. https://doi.org/10.1016/j.prostaglandins.2006.05.019.
- Clarke R, Derry S, Moore RA. Single dose oral etoricoxib for acute postoperative pain in adults. Cochrane Database Syst Rev. 2014;2(5):CD004309. https://doi.org/10.1002/14651858.CD004309.pub3.
- Close BR. Tramadol: does it have a role in emergency medicine? Emerg Med Australas. 2005;17(1):73-83. https://doi. org/10.1111/j.1742-6723.2005.00671.x.
- Colli A, Conte D, Valle SD, Sciola V, Fraquelli M. Meta-analysis: nonsteroidal anti-inflammatory drugs in biliary colic. Aliment Pharmacol Ther. 2012;35(12):1370-8. https://doi.org/10.1111/j.1365-2036.2012.05115.x.
- Connor-Ballard PA. Understanding and managing burn pain: part 1. Am J Nurs. 2009;109(4):48-56. https://doi.org/10.1097/01. NAJ.0000348604.47231.68.
- Connor-Ballard PA. Understanding and managing burn pain: part 2. Am J Nurs. 2009;109(5):54-62. https://doi.org/10.1097/01. NAJ.0000351510.77627.db.
- Costa A, Antonaci F, Ramusino MC, Nappi G. The neuropharmacology of cluster headache and other trigeminal autonomic cephalalgias. Curr Neuropharmacol. 2015;13(3):304-23. https://doi.org/10.2174/1570159X13666150309233556.
- Cregg R, Anwar S, Farquhar-Smith P. Persistent postsurgical pain. Curr Opin Support Palliat Care. 2013;7(2):144-52. https://doi.org/10.1097/ SPC.0b013e328360b09e.
- Dahaba AA, Grabner T, Rehak PH, List WF, Metzler H. Remifentanil versus morphine analgesia and sedation for mechanically ventilated critically ill patients: a randomized double blind study. Anesthesiology. 2004;101(3):640-6. https://doi. org/10.1097/00000542-200409000-00012.
- Daoust R, Paquet J, Cournoyer A, et al. Quantity of opioids consumed following an emergency department visit for acute pain: a Canadian prospective cohort study. BMJ Open. 2018;8(9):e022649. https://doi.org/10.1136/bmjopen-2018-022649.
- Davis MP. Drug management of visceral pain: concepts from basic research. Pain Res Treat. 2012;1-18. https://doi. org/10.1155/2012/265605.
- De Castro RJ, Leal PC, Sakata RK. Pain management in burn patients. Braz J Anesthesiol. 2013;63(1):149-53. https://doi.org/10.1016/ S0034-7094(13)70206-X.
- De Oliveira GS Jr, Almeida MD, Benzon HT, McCarthy RJ. Perioperative single dose systemic dexamethasone for postoperative pain: a meta-analysis of randomized controlled trials. Anesthesiology. 2011;115(3):575-88. https://doi.org/10.1097/ALN.0b013e31822a24c2.
- Delvaux B, Ryckwaert Y, Van Boven M, De Kock M, Capdevila X. Remifentanil in the intensive care unit: tolerance and acute withdrawal syndrome after prolonged sedation. Anesthesiology. 2005;102(6):1281-2. https://doi.org/10.1097/00000542-200506000-00030.
- Devabhakthuni S, Armahizer MJ, Dasta JF, Kane-Gill SL. Analgosedation: a paradigm shift in intensive care unit sedation practice. Ann Pharmacother. 2012;46(4):530-40. https://doi.org/10.1345/aph.1Q525.
- Diener HC, Limmroth V. Acute management of migraine: triptans and beyond. Curr Opin Neurol. 1999;12(3):261-7. https://doi. org/10.1097/00019052-199906000-00004.
- Do TP, Remmers A, Schytz HW, et al. Red and orange flags for secondary headaches in clinical practice: SNNOOP10 list. Neurology. 2019;92(3):134-44. https://doi.org/10.1212/WNL.0000000000006697.
- Dosenovic S, Kadic AJ, Miljanovic M, et al. Interventions for neuropathic pain: an overview of systematic reviews. Anesth Analg. 2017;125(2):643-52. https://doi.org/10.1213/ANE.0000000000001998.
- Druart-Blazy A, Pariente A, Berthelemy P, Arotcarena R. The underestimated role of opiates in patients with suspected sphincter of Oddi dysfunction after cholecystectomy. Gastroen Clin Biol. 2005;29(12):1220-3. https://doi.org/10.1016/S0399-8320(05)82204-3.
- Dubinsky RM, Kabbani H, El-Chami Z, Boutwell C, Ali H, Quality standards subcommittee of the American Academy of Neurology. Practice parameter: treatment of postherpetic neuralgia: an evidence-based report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2004;63(6):959-65. https://doi.org/10.1212/01.WNL.0000140708.62856.72.
- Duehmke RM, Derry S, Wiffen PJ, et al. Tramadol for neuropathic pain in adults. Cochrane Database Syst Rev. 2017;6(6):CD003726. https:// doi.org/10.1002/14651858.CD003726.pub4.
- Dula DJ, Anderson R, Wood GC. A prospective study comparing i.m. ketorolac with i.m. meperidine in the treatment of acute biliary colic. J Emerg Med. 2001;20(2):121-4. https://doi.org/10.1016/S0736-4679(00)00311-5.
- Ezike HA, Odiakosa MC. Oral ketamine for wound care procedures in adult patients with burns. South Afr J Anaesth Analg. 2011;17(3):242- 8. https://doi.org/10.1080/22201173.2011.10872785.
- Firouzian A, Alipour A, Dezfouli HR, et al. Does lidocaine as an adjuvant to morphine improve pain relief in patients presenting to the ED with acute renal colic? A double-blind, randomized controlled trial. Am J Emerg Med. 2016;34(3):443-8. https://doi.org/10.1016/j. ajem.2015.11.062
- Flake ZA, Scalley RD, Bailey AG. Practical selection of antiemetics. Am Fam Physician. 2004;69(5):1169-74.
- Forbes RB. Acute headache. Ulster Med J. 2014;83(1):3-9.
- Francis GJ, Becker WJ, Pringsheim TM. Acute and preventive pharmacologic treatment of cluster headache. Neurology. 2010;75(5):463-73. https://doi.org/10.1212/WNL.0b013e3181eb58c8.
- Garg N, Panda NB, Gandhi KA, et al. Comparison of small dose ketamine and dexmedetomidine infusion for postoperative analgesia in spine surgery - a prospective randomized double-blind placebo controlled study. J Neurosurg Anesthesiol. 2016;28(1):27-31. https://doi. org/10.1097/ANA.0000000000000193.
- Garrubba C, Donkers K. An updated approach to treating and preventing herpes zoster. JAAPA. 2013;26(12):56-9. https://doi. org/10.1097/01.JAA.0000438245.33074.a3.
- Gerstein NS, Schulman PM, Gerstein WH, Petersen TR, Tawil I. Should more patients continue aspirin therapy perioperatively? Clinical impact of aspirin withdrawal syndrome. Ann Surg. 2012;255(5):811-9. https://doi.org/10.1097/SLA.0b013e318250504e.
- Gilron I. Gabapentin and pregabalin for chronic neuropathic and early postsurgical pain: current evidence and future directions. Curr Opin in Anaesthesiol. 2007;20(5):456-72. https://doi.org/10.1097/ACO.0b013e3282effaa7.
- Gommers D, Bakker J. Medications for analgesia and sedation in the intensive care unit: an overview. Crit Care. 2008;12(3):S4. https://doi. org/10.1186/cc6150.
- Goodman CW, Brett AS. A clinical overview of off-label use of gabapentinoid drugs. JAMA Intern Med. 2019;179(5):695-701. https://doi. org/10.1001/jamainternmed.2019.0086.
- Graff-Radford SB. Facial pain. Curr Opin Neurol. 2000;13(3):291-6. https://doi.org/10.1097/NRL.0b013e31819827d8.
- Greenwood-Van Meerveld B, Johnson AC. Stress-induced chronic visceral pain of gastrointestinal origin. Front Syst Neurosci. 2017;11:86. https://doi.org/10.3389/fnsys.2017.00086.
- Grothe DR, Scheckner B, Albano D. Treatment of pain syndromes with venlafaxine. Pharmacotherapy. 2004;24(5):621-9. https://doi. org/10.1592/phco.24.6.621.34748.
- Guillen-Astete CA, Cardona-Carballo C, De la Casa-Resino C. Tapentadol versus tramadol in the management of low back pain in the emergency department: impact of use on the need for reassessments. Medicine. 2017;96(45):e8403. https://doi.org/10.1097/ MD.0000000000008403.
- Happich M, Schneider E, Boess FG, et al. Effectiveness of duloxetine compared with pregabalin and gabapentin in diabetic peripheral neuropathic pain: results from a German observational study. Clin J Pain. 2014;30(10):875-85. https://doi.org/10.1097/ AJP.0000000000000057.
- Harmon KG, Hawley C. Physician prescribing patterns of oral corticosteroids for musculoskeletal injuries. J Am Board Fam Pract. 2003;16(3):209-12. https://doi.org/10.3122/jabfm.16.3.209.
- Harris RC. COX-2 and the kidney. J Cardiovasc Pharmacol. 2006;47 Suppl 1:S37-42. https://doi.org/10.1097/00005344-200605001-00007.
- Hayhurst CJ, Durieux ME. Differential opioid tolerance and opioid-induced hyperalgesia: a clinical reality. Anesthesiology. 2016;124(2):483-8. https://doi.org/10.1097/ALN.0000000000000963.
- Headache Classification Subcommittee of the International Headache Society. First level of The International Classification of Headache Disorders, 2nd ed. Cephalalgia. 2004;24(Suppl 1):9-160.
- Heit HA, Gourlay DL. Buprenorphine new tricks with an old molecule for pain management. Clin J Pain. 2008;24:93-7. https://doi. org/10.1097/AJP.0b013e31815ca2b4.
- Hirst A, Knight C, Hirst M, Dunlop W, Akehurst R. Tramadol and the risk of fracture in an elderly female population: a cost utility assessment with comparison to transdermal buprenorphine. Eur J Health Econ. 2016;17:217-27. https://doi.org/10.1007/ s10198-015-0673-1.
- Holle D, Naegel S, Obermann M. Pathophysiology of hypnic headache. Cephalalgia. 2014;34(10):806-12. https://doi. org/10.1177/0333102414535996.
- Hossain SM, Hussain SM, Ekram AR. Duloxetine in painful diabetic neuropathy: a systematic review. Clin J Pain. 2016;32(11):1005-10. https://doi.org/10.1097/AJP.0000000000000343.
- Hurley RW, Adams MC, Benzon HT. Neuropathic pain: treatment guidelines and updates. Curr Opin Anaesthesiol. 2013;26(5):580-7. https://doi.org/10.1097/ACO.0b013e328363b4bf.
- Hyllested M, Jones S, Pedersen JL, Kehlet H. Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review. Br J Anaesth. 2002;88(2):199-214. https://doi.org/10.1093/bja/88.2.199.
- Ip EJ, Barnett MJ, Tenerowicz MJ, et al. Women and anabolic steroids: an analysis of a dozen users. Clin J Sport Med. 2010;20(6):475-81. https://doi.org/10.1097/JSM.0b013e3181fb5370.
- Jalili M, Bahreini M, Doosti-Irani A, et al. Ketamine-propofol combination (ketofol) vs propofol for procedural sedation and analgesia: systematic review and meta-analysis. Am J Emerg Med. 2016;34(3):558-69. https://doi.org/10.1016/j.ajem.2015.12.074.
- Javery KB, Ussery TW, Steger HG, Colclough GW. Comparison of morphine and morphine with ketamine for postoperative analgesia. Can J Anesth. 1996;43(3):212-5. https://doi.org/10.1007/BF03011736.
- Jennings PA, Cameron P, Bernard S, et al. Morphine and ketamine is superior to morphine alone for out-of-hospital trauma analgesia: a randomized controlled trial. Ann Emerg Med. 2012;59(6):497-503. https://doi.org/10.1016/j.annemergmed.2011.11.012.
- Jesani J, Simerson D. Pharmacologic management of acute migraines in the emergency department. Adv Emerg Nurs J. 2019;41(2):150- 62. https://doi.org/10.1097/TME.0000000000000229.
- Jiao JM, So E, Jebakumar J, et al. Chronic pain disorders in HIV primary care: clinical characteristics and association with healthcare utilization. Pain. 2016;157(4):931-7. https://doi.org/10.1097/j.pain.0000000000000462.
- Johnson J, Weinryb J. Safe pharmacologic treatment strategies for osteoarthritis pain in African Americans with hypertension, and renal and cardiac disease. J Natl Med Assoc. 2006;98(7):1126-35.
- Jones LM, Uribe AA, Coffey R, et al. Pregabalin in the reduction of pain and opioid consumption after burn injuries: a preliminary, randomized, double-blind, placebo-controlled study. Medicine. 2019;98(18):e15343. https://doi.org/10.1097/MD.0000000000015343.
- Judkins K, Clark L. Managing the pain of burn wounds. Wounds. 2010;6(1):110-8.
- Kalso E. How different is oxycodone from morphine? Pain. 2007;132(3):227-8. https://doi.org/10.1016/j.pain.2007.09.027.
- Kamins J, Charles A. Posttraumatic headache: Basic mechanisms and therapeutic targets. Headache. 2018;58(6):811-26. https://doi. org/10.1111/head.13312.
- Kaniecki RG. Tension-type headache. Continuum. 2012;18(4):823-34. https://doi.org/10.1212/01.CON.0000418645.32032.32.
- Katz D, Beilin Y. Review of the alternatives to epidural blood patch for treatment of postdural puncture headache in the parturient. Anesth Analg. 2017;124(4):1219-28. https://doi.org/10.1213/ANE.0000000000001840.
- Kern KU, Nowack W, Poole C. Treatment of neuropathic pain with the capsaicin 8% patch: is pretreatment with lidocaine necessary? Pain Pract. 2014;14(2):E42-50. https://doi.org/10.1111/papr.12143.
- Kirkby NS, Chan MV, Zaiss AK, et al. Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-kappaB and NFAT transcriptional pathways. Proc Natl Acad Sci USA. 2016;113(2):434-9. https://doi.org/10.1073/pnas.1517642113.
- Kornick CA, Santiago-Palma J, Schulman G, et al. A safe and effective method for converting patients from transdermal to intravenous fentanyl for the treatment of acute cancer-related pain. Cancer. 2003;97(12):3121-4. https://doi.org/10.1002/cncr.11457.
- Kumar A, Deed JS, Bhasin B, Kumar A, Thomas S. Comparison of the effect of diclofenac with hyoscine-N-butylbromide in the symptomatic treatment of acute biliary colic. ANZ J Surg. 2004;74(7):573-6. https://doi.org/10.1111/j.1445-2197.2004.03058.x.
- Kundra P, Velayudhan S, Krishnamachari S, Gupta SL. Oral ketamine and dexmedetomidine in adults’ burns wound dressing - a randomized double blind cross over study. Burns. 2013;39(6):1150-6. https://doi.org/10.1016/j.burns.2013.02.012.
- Kurdi MS, Hearth KA, Deva RS. Ketamine: current applications in anesthesia, pain, and critical care. Anesth Essays Res. 2014;8(3):283-90. https://doi.org/10.4103/0259-1162.143110.
- Kvarnstrom A, Karlsten R, Quiding H, Emanuelsson BM, Gordh T. The effectiveness of intravenous ketamine and lidocaine on peripheral neuropathic pain. Acta Anaesthesiol Scand. 2003;47(7):868-77. https://doi.org/10.1034/j.1399-6576.2003.00187.x.
- Larsen A, Piepgras D, Chyatte D, Rizzolo D. Trigeminal neuralgia: diagnosis and medical and surgical management. JAAPA. 2011;24(7):20-5. https://doi.org/10.1097/01720610-201107000-00005.
- Lauritzen M. Cortical spreading depression in migraine. Cephalalgia. 2001;21(7):757-60. https://doi.org/10.1177/033310240102100704.
- Lawrence EC. Diagnosis and management of migraine headaches. South Med J. 2004;97(11):1069-77.
- Lay CM. Low cerebrospinal fluid pressure headache. Curr Treat Options Neurol. 2002;4:357-63. https://doi.org/10.1007/s11940-002-0046-9.
- Li S, Guo J, Li F, et al. Pregabalin can decrease acute pain and morphine consumption in laparoscopic cholecystectomy patients: a meta-analysis of randomized controlled trials. Medicine. 2017;96(21):e6982. https://doi.org/10.1097/MD.0000000000006982.
- Liang JF, Wang SJ. Hypnic headache: a review of clinical features, therapeutic options and outcomes. Cephalalgia. 2014;34(10):795-805. https://doi.org/10.1177/0333102414537914.
- Lipton RB, Bigal ME, Steiner TJ, Silberstein SD, Olesen J. Classification of primary headaches. Neurology. 2004;63(3):427-35. https://doi. org/10.1212/01.WNL.0000133301.66364.9B.
- Liu B, Liu R, Wang L. A meta-analysis of the preoperative use of gabapentinoids for the treatment of acute postoperative pain following spinal surgery. Medicine. 2017;96(37):e8031. https://doi.org/10.1097/MD.0000000000008031.
- Long B, April MD. Are nonsteroidal anti-inflammatory drugs efficacious in relieving biliary colic pain? Ann Emerg Med. 2017;70(6):822-4. https://doi.org/10.1016/j.annemergmed.2017.03.012.
- Low Y, Clarke CF, Billy K, Huh BK. Opioid-induced hyperalgesia: a review of epidemiology, mechanisms and management. Singapore Med J. 2012;53(5):357-60.
- Majdinasab N, Kaveyani H, Azizi M. A comparative double-blind randomized study on the effectiveness of duloxetine and gabapentin on painful diabetic peripheral polyneuropathy. Drug Des Devel Ther. 2019;13:1985-92. https://doi.org/10.2147/DDDT.S185995.
- Mao J, Chen LL. Systemic lidocaine for neuropathic pain relief. Pain. 2000;87:7-17. https://doi.org/10.1016/S0304-3959(00)00229-3.
- Marmura MJ, Silberstein SD. Headaches caused by nasal and paranasal sinus disease. Neurol Clin. 2014;32(2):507-23. https://doi. org/10.1016/j.ncl.2013.11.001.
- Matava MJ. Injectable nonsteroidal anti-inflammatory drugs in sport. Clin J Sport Med. 2018;28(5):443-50. https://doi.org/10.1097/ JSM.0000000000000602.
- McGeeney BE. Cluster headache pharmacotherapy. Am J Ther. 2005;12(4):351-8. https://doi.org/10.1097/01.mjt.0000174351.20389.99.
- Mehallo CJ, Drezner JA, Bytomski JR. Practical management: nonsteroidal antiinflammatory drug (NSAID) use in athletic injuries. Clin J Sport Med. 2006;16(2):170-4. https://doi.org/10.1097/00042752-200603000-00015.
- Miotto K, Cho AK, Khalil MA, et al. Trends in tramadol: pharmacology, metabolism, and misuse. Anesth Analg. 2017;124(1):44-51. https:// doi.org/10.1213/ANE.0000000000001683.
- Miranda HF, Puig MM, Prieto JC, Pinardi G. Synergism between paracetamol and nonsteroidal anti-inflammatory drugs in experimental acute pain. Pain. 2006;121:22-8. https://doi.org/10.1016/j.pain.2005.11.012.
- Moore RA, Derry S, Wiffen PJ, Straube S, Bendtsen L. Evidence for efficacy of acute treatment of episodic tension-type headache: methodological critique of randomised trials for oral treatments. Pain. 2014;155(11):2220-8. https://doi.org/10.1016/j.pain.2014.08.009.
- Muellejans B, Matthey T, Scholpp J, Schill M. Sedation in the intensive care unit with remifentanil/propofol versus midazolam/fentanyl: a randomised, open-label, pharmacoeconomic trial. Crit Care. 2006;10(3):R91. https://doi.org/10.1186/cc4939.
- Mulla SM, Wang L, Khokhar R, et al. Management of central poststroke pain: systematic review of randomized controlled trials. Stroke. 2015;46(10):2853-60. https://doi.org/10.1161/STROKEAHA.115.010259.
- Murphy DB, Sutton JA, Prescott LF, Murphy MB. Opioid-induced delay in gastric emptying: a peripheral mechanism in humans. Anesthesiology. 1997;87(4):765-70. https://doi.org/10.1097/00000542-199710000-00008.
- Nalamachu SR. Opioid rotation in clinical practice. Adv Ther. 2012;29(10):849-63. https://doi.org/10.1007/s12325-012-0051-7.
- Nalamachu SR. Opioid rotation with extended-release opioids: where should we begin? Int J Gen Med. 2012;5:11-7. https://doi. org/10.2147/IJGM.S24287.
- Narayanan M, Venkataraju A, Jennings J. Analgesia in intensive care: part 1. BJA Education. 2016;16(2):72-8. https://doi.org/10.1093/ bjaceaccp/mkv018.
- Nedelec B, La Salle L. Postburn itch: a review of the literature. Wounds. 2018;30(1):E118-24.
- Nie Y, Liu Y, Luo Q, Huang S. Effect of dexmedetomidine combined with sufentanil for post-caesarean section intravenous analgesia. Eur J Anaesthesiol. 2014;31:197-20. https://doi.org/10.1097/EJA.0000000000000011.
- Nielsena RV, Siegelb H, Fomsgaarda JS, et al. Preoperative dexamethasone reduces acute but not sustained pain after lumbar disk surgery: a randomized, blinded, placebo-controlled trial. Pain. 2015;156(12):2538-44. https://doi.org/10.1097/j.pain.0000000000000326.
- Norman AT, Judkins KC. Pain in the patient with burns. BJA Education. 2004;4(2):57-61. https://doi.org/10.1093/bjaceaccp/mkh016.
- Nossaman VE, Ramadhyani U, Kadowitz PJ, Nossaman BD. Advances in perioperative pain management: use of medications with dual analgesic mechanisms, tramadol & tapentadol. Anesthesiology Clin. 2010;28:647-66. https://doi.org/10.1016/j.anclin.2010.08.009.
- Obermann M. Treatment options in trigeminal neuralgia. Ther Adv Neurol Disord. 2010;3(2):107-15. https://doi. org/10.1177/1756285609359317.
- Olkkola KT, Hagelberg NM. Oxycodone: new ‘old’ drug. Curr Opin Anesthesiol. 2009;22(4):459-62. https://doi.org/10.1097/ ACO.0b013e32832bc818.
- Ong CKS, Seymour RA, Lirk P, Merry AF. Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain. Anesth Analg. 2010;110(4):1170-9. https://doi.org/10.1213/ ANE.0b013e3181cf9281.
- Oscier CD, Milner QJW. Peri-operative use of paracetamol. Anaesthesia. 2009;64:65-72. https://doi.org/10.1111/j.1365-2044.2008.05674.x.
- Pai A, Heining M. Ketamine. BAJ Education. 2007;7(2):59-63. https://doi.org/10.1093/bjaceaccp/mkm008.
- Park G, Lane M, Rogers S, Bassett P. A comparison of hypnotic and analgesic based sedation in a general intensive care unit. Br J Anaesth. 2007;98(1):76-82. https://doi.org/10.1093/bja/ael320.
- Parsons B, Emir B, Knapp L. Examining the time to improvement of sleep interference with pregabalin in patients with painful diabetic peripheral neuropathy and postherpetic neuralgia. Am J Ther. 2015;22(4):257-68. https://doi.org/10.1097/MJT.0000000000000100.
- Pathan SA, Mitra B, Cameron PA. A systematic review and meta-analysis comparing the efficacy of nonsteroidal anti-inflammatory drugs, opioids, and paracetamol in the treatment of acute renal colic. Eur Urol. 2018;73(4):583-95. https://doi.org/10.1016/j.eururo.2017.11.001.
- Patrono C. Cardiovascular effects of cyclooxygenase-2 inhibitors: a mechanistic and clinical perspective. Br J Clin Pharmacol. 2016;82(4):957-64. https://doi.org/10.1111/bcp.13048.
- Perahia DG, Pritchett YL, Desaiah D, Raskin J. Efficacy of duloxetine in painful symptoms: an analgesic or antidepressant effect? Int Clin Psychopharmacol. 2006;21(6):311-7. https://doi.org/10.1097/01.yic.0000224782.83287.3c.
- Peskar BM. Role of cyclooxygenase isoforms in gastric mucosal defence. J Physiol Paris. 2001;95(1-6):3-9. https://doi.org/10.1016/ S0928-4257(01)00003-1.
- Pleuvry BJ. Physiology and pharmacology of nausea and vomiting. Anaesth Intensive Care Med. 2015;16(9):462-6. https://doi. org/10.1016/j.mpaic.2015.06.018.
- Pogatzki-Zahn E, Chandrasena C, Schug SA. Nonopioid analgesics for postoperative pain management. Curr Opin Anesthesiol. 2014;27(5):513-9. https://doi.org/10.1097/ACO.0000000000000113.
- Poonai N, Canton K, Ali S, et al. Intranasal ketamine for procedural sedation and analgesia in children: A systematic review. PLoS ONE. 2017;12(3):e0173253. https://doi.org/10.1371/journal.pone.0173253.
- Poulopoulos M, Finelli PF. Neurological complications with acute sphenoid sinusitis a surgical emergency? Neurocrit Care. 2007;7(2):169- 71. https://doi.org/10.1007/s12028-007-0036-6.
- Prieto-Garcia L, Pericacho M, Sancho-Martinez SM, et al. Mechanisms of triple whammy acute kidney injury. Pharmacol Ther. 2016;167:132-45. https://doi.org/10.1016/j.pharmthera.2016.07.011.
- Procter NJ, Lamacraft G, Joubert G. Intravenous paracetamol - waste not, want not: a retrospective audit on the appropriate use of intravenous paracetamol at Universitas Academic Hospital Complex - Bloemfontein. South Afr J Anaesth Analg. 2018;24(1):22-8. https:// doi.org/10.1080/22201181.2018.1426208.
- Rastogi R, Swarm RA, Patel TA, Riou B. Case scenario: opioid association with serotonin syndrome: implications to the practitioners. Anesthesiology. 2011;115(6):1291-8. https://doi.org/10.1097/ALN.0b013e31823940c0.
- Remerand F, Le Tendre C, Baud A, et al. The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study. Anesth Analg. 2009;109(6):1963-71. https://doi.org/10.1213/ANE.0b013e3181bdc8a0.
- Reuben SS. Update on the role of nonsteroidal anti-inflammatory drugs and coxibs in the management of acute pain. Curr Opin Anesthesiol. 2007;20(5):440-50. https://doi.org/10.1097/ACO.0b013e3282effb1d.
- Rhalimi M, Helou R, Jaecker P. Medication use and increased risk of falls in hospitalized elderly patients: a retrospective, case-control study. Drugs Aging. 2009;26(10):847-52. https://doi.org/10.2165/11317610-000000000-00000.
- Ripple MG, Pestaner JP, Levine BS, Smialek JE. Lethal combination of tramadol and multiple drugs affecting serotonin. Am J Foren Med Path. 2000;21(4):370-4. https://doi.org/10.1097/00000433-200012000-00015.
- Rowe K, Fletcher S. Sedation in the intensive care unit. BJA Education. 2008;8(2):50-5. https://doi.org/10.1093/bjaceaccp/mkn005.
- Rozen TD. Emergency department and inpatient management of status migrainosus and intractable headache. Continuum. 2015;21(4 Headache):1004-17. https://doi.org/10.1212/CON.0000000000000191.
- Samuels LA. Pharmacotherapy update: Hyoscine butylbromide in the treatment of abdominal spasms. Clin Med Insights Ther. 2009;1:647- 55. https://doi.org/10.4137/CMT.S1134.
- Santonocito C, Noto A, Crimi C, Sanfilippo F. Remifentanil-induced postoperative hyperalgesia: current perspectives on mechanisms and therapeutic strategies. Local Reg Anesth. 2018;11:15-21. https://doi.org/10.2147/LRA.S143618.
- Shah HR, Kodack E, Walker J III. Neuropathic pain: a review of pathophysiology, presentation, and management. Topics in Pain Management. 2020;35(8):1-7. https://doi.org/10.1097/01.TPM.0000656628.38396.3a.
- Sheridan R. Outpatient burn care in the emergency department. Pediatr Emerg Care. 2005;21(7):449-56. https://doi.org/10.1097/01. pec.0000169438.29315.fe.
- Sherman S, Gottlieb K, Uzer MF, et al. Effects of meperidine on the pancreatic and biliary sphincter. Gastrointest Endosc. 1996;44(3):239- 42. https://doi.org/10.1016/S0016-5107(96)70158-X.
- Shillingburg A, Kanate AS, Hamadani M, et al. Treatment of severe mucositis pain with oral ketamine mouthwash. Support Care Cancer. 2017;25(7):2215-19. https://doi.org/10.1007/s00520-017-3627-6.
- Shoja MM, Oyesiku NM, Griessenauer CJ, et al. Anastomoses between lower cranial and upper cervical nerves: a comprehensive review with potential significance during skull base and neck operations, part I: trigeminal, facial, and vestibulocochlear nerves. Clin Anat. 2014;27(1):118-30. https://doi.org/10.1002/ca.22340.
- Shoja MM, Oyesiku NM, Shokouhi G, et al. Anastomoses between lower cranial and upper cervical nerves: a comprehensive review with potential significance during skull base and neck operations, Part II: Glossopharyngeal, vagus, accessory, and hypoglossal nerves and cervical spinal nerves 1-4. Clin Anat. 2014;27(1):131-44. https://doi.org/10.1002/ca.22342.
- Siddall PJ, Cousins MJ, Otte A, et al. Pregabalin in central neuropathic pain associated with spinal cord injury: a placebo-controlled trial. Neurology. 2006;67(10):1792-800. https://doi.org/10.1212/01.wnl.0000244422.45278.ff.
- Sim V, Hawkins S, Gave AA, et al. How low can you go: achieving postoperative outpatient pain control without opioids. J Trauma Acute Care Surg. 2019;87(1):100-3. https://doi.org/10.1097/TA.0000000000002295.
- Simpson DM, McArthur JC, Olney R, et al. Lamotrigine HIV neuropathy study team. Lamotrigine for HIV-associated painful sensory neuropathies: a placebo-controlled trial. Neurology. 2003;60(9):1508-14. https://doi.org/10.1212/01.WNL.0000063304.88470.D9.
- Simpson DM, Rice AS, Emir B, et al. A randomized, double-blind, placebo-controlled trial and open-label extension study to evaluate the efficacy and safety of pregabalin in the treatment of neuropathic pain associated with human immunodeficiency virus neuropathy. Pain. 2014;155(10):1943-54. https://doi.org/10.1016/j.pain.2014.05.027.
- Simpson DM, Schifitto G, Clifford DB, et al. 1066 HIV neuropathy study group. Pregabalin for painful HIV neuropathy: a randomized, double-blind, placebo-controlled trial. Neurology. 2010;74(5):413-20. https://doi.org/10.1212/WNL.0b013e3181ccc6ef.
- Sinatra RS, Jahr JS, Reynolds LW, et al. Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery. Anesthesiology. 2005;102:822-31. https://doi. org/10.1097/00000542-200504000-00019.
- Sindrup SH, Jensen TS. Pharmacotherapy of trigeminal neuralgia. Clin J Pain. 2002;18(1):22-7. https://doi. org/10.1097/00002508-200201000-00004.
- Singh P, Yoon SS, Kuo B. Nausea: a review of pathophysiology and therapeutics. Ther Adv Gastroenterol. 2016;9(1):98-112. https://doi. org/10.1177/1756283X15618131.
- Sinha S, Schreiner AJ, Biernaskie J, Nickerson D, Gabriel VA. Treating pain on skin graft donor sites: Review and clinical recommendations. J Trauma Acute Care Surg. 2017;83(5):954-64. https://doi.org/10.1097/TA.0000000000001615.
- Skolarikos A. Medical treatment of urinary stones. Curr Opin Urol. 2018;28(5):403-7. https://doi.org/10.1097/MOU.0000000000000523.
- Spierings EL. Pathogenesis of the migraine attack. Clin J Pain. 2003;19(4):255-62. https://doi.org/10.1097/00002508-200307000-00009.
- Sriperumbuduri S, Hiremath S. The case for cautious consumption: NSAIDs in chronic kidney disease. Curr Opin Nephrol Hypertens. 2019;28:163-70. https://doi.org/10.1097/MNH.0000000000000473.
- Steinberg PL, Chang SL. Pain relief for acute urolithiasis: the case for non-steroidal anti-inflammatory drugs. Drugs. 2016;76(10):993-7. https://doi.org/10.1007/s40265-016-0595-y.
- Stoehr JD, Essary AC, Ou C, Ashby R, Sucher M. The risk of tramadol abuse and dependence: findings in two patients. JAAPA. 2009;22(7):31-5. https://doi.org/10.1097/01720610-200907000-00008.
- Sun L, Zhu X, Zou J, Li Y, Han W. A systematic review and meta-analysis. Medicine. 2018;97(6);e9751. https://doi.org/10.1097/ MD.0000000000009751.
- Takahashi M, Katayama Y, Takada H, Kuwayama H, Terano A. The effect of NSAIDs and COX-2 specific inhibitor on Helicobacter pylori-induced PGE2 and HGF in human gastric fibroblasts. Aliment Pharm Ther. 2000;14(Suppl 1):44-9. https://doi. org/10.1046/j.1365-2036.2000.014s1044.x.
- Tepper SJ. Cranial neuralgias. Continuum. 2018;24(4, Headache):1157-78. https://doi.org/10.1212/CON.0000000000000637.
- Tfelt-Hansen PC. Does sumatriptan cross the blood-brain barrier in animals and man? J Headache Pain. 2010;11:5-12. https://doi. org/10.1007/s10194-009-0170-y
- Tremont-Lukats IW, Hutson PR, Backonja M. A randomized double-masked, placebo-controlled pilot trial of extended IV lidocaine infusion for relief of ongoing neuropathic pain. Clin J Pain. 2006;22(3):266-71. https://doi.org/10.1097/01.ajp.0000169673.57062.40.
- Treu CN, Groth CM, Patel JH. The use of continuous ketamine for analgesia and sedation in critically ill patients with opioid abuse: a case series. J Crit Care Med. 2017;3(4):148-52. https://doi.org/10.1515/jccm-2017-0026.
- Vadivelu N, Chang D, Helander EM, et al. Ketorolac, oxymorphone, tapentadol, and tramadol: a comprehensive review. Anesthesiol Clin. 2017;35(2):e1-e20. https://doi.org/10.1016/j.anclin.2017.01.001.
- Venkataraju A, Narayanan M. Analgesia in intensive care: part 2. BJA Education. 2016;16(12):397-404. https://doi.org/10.1093/bjaed/ mkw021.
- Villesen HH, Banning A, Petersen RH, et al. Pharmacokinetics of morphine and oxycodone following intravenous administration in elderly patients. Ther Clin Risk Manag. 2007;3(5):961-7.
- Votey SR, Bosse GM, Bayer MJ, Hoffman JR. Flumazenil: a new benzodiazepine antagonist. Ann Emerg Med. 1991;20:181-8. https://doi. org/10.1016/S0196-0644(05)81219-3.
- Wasiak J, Mahar PD, Paul E, et al. Inhaled methoxyflurane for pain and anxiety relief during burn wound care procedures: an Australian case series. Int Wound J. 2014;11(1):74-8. https://doi.org/10.1111/j.1742-481X.2012.01067.x.
- Wehrmann T, Rausch D, Seiler KU, Brennscheidt U, Caspary WF. Tilidine does not affect human sphincter of Oddi motility-randomized, controlled study. Aliment Pharmocol Ther. 1997;11:987-92. https://doi.org/10.1046/j.1365-2036.1997.00221.x.
- White PF. Changing role of COX-2 inhibitors in the perioperative period: is parecoxib really the answer? Anesth Analg. 2005;100(5):1306-8. https://doi.org/10.1213/01.ANE.0000158607.90390.01.
- White WB. Cardiovascular effects of the cyclooxygenase inhibitors. Hypertension. 2007;49(3):408-18. https://doi.org/10.1161/01. HYP.0000258106.74139.25.
- Whittle BJ. COX-1 and COX-2 products in the gut: therapeutic impact of COX-2 inhibitors. Gut. 2000;47(3):320-5. https://doi.org/10.1136/ gut.47.3.320.
- WHO. Tramadol update review report. Expert committee on drug dependence thirty‐sixth meeting, Geneva; 2014.
- Wilhelm IR, Tzabazis A, Likar R, Sittl R, Griessinger N. Long-term treatment of neuropathic pain with a 5% lidocaine medicated plaster. Eur J Anaesthesiol. 2010;27(2):169-73. https://doi.org/10.1097/EJA.0b013e328330e989.
- Willman EV, Andolfatto G. A prospective evaluation of “ketofol” (ketamine/propofol combination) for procedural sedation and analgesia in the emergency department. Ann Emerg Med. 2007;49(1):23-30. https://doi.org/10.1016/j.annemergmed.2006.08.002.
- Yang F, Lin Q, Dong L, Gao X, Zhang S. Efficacy of 8 different drug treatments for patients with trigeminal neuralgia: a network meta-analysis. Clin J Pain. 2018;34(7):685-90. https://doi.org/10.1097/AJP.0000000000000577.
- Zeidan A, Mazoit JX, Abdullah MA, et al. Median effective dose (ED50) of paracetamol and morphine for postoperative pain: a study of interaction. Br J Anaesth. 2014;112(1):118-23. https://doi.org/10.1093/bja/aet306.
- Zilliox LA. Neuropathic pain. Continuum. 2017;23(2, Selected Topics in Outpatient Neurology):512-32. https://doi.org/10.1212/ CON.0000000000000462.
South African Society of Anaesthesiologists (SASA) Guidelines for the Management of Acute Pain in Specific Scenarios 2022