Renal Calculi
Standard Treatment Guidelines and Essential Medicines List for South Africa, Hospital Level, Adults 2019 Edition
N20.0-2/N20.9/N21.0/N21.8/N21.9
DESCRIPTION
A kidney stone or calculus which has formed in the renal tract, i.e. pelvis, ureters or bladder, as a result of urine which is supersaturated with a stone-forming salt.
Clinical features of obstructing urinary stones may include:
- sudden onset of acute colic, localized to the flank, causing the patient to move constantly,
- nausea and vomiting,
- referred pain to the scrotum or labium as the stone moves down the ureter.
Urinalysis usually reveals microscopic or macroscopic haematuria.
Stones may be passed spontaneously, after medical or invasive treatment.
If available, collect the stones and send to the laboratory for analysis.
GENERAL MEASURES
Acute stage:
- Oral fluids administered liberally.
- Intravenous fluids to ensure adequate hydration and urine flow.
To prevent recurrence:
- Avoid dehydration.
- If recurrences occur, consult a specialist.
MEDICINE TREATMENT
Analgesia for renal colic:
- NSAID, oral: e.g.
- Ibuprofen, oral, 400 mg 8 hourly with meals.
LoE:IIbxli
Note:
Avoid NSAIDs if renal impairment is present or suspected.
If patient is vomiting:
- Diclofenac, IM, 75 mg as a single dose.
LoE:IVb
AND/OR
- Tramadol, IM, 50–100 mg, 4-6 hourly.
LoE:IVb
OR
- Morphine, IV, to a total maximum dose of 10 mg (See Appendix II: Prescribing Information for Specific Medicines, for individual dosing and monitoring for response and toxicity).
Currently, there is no convincing evidence to support the use of hyoscine in this setting.
For vomiting:
- Metoclopramide, IM, 10 mg 8 hourly.
LoE:IVb
REFERRAL
- In acute setting for suspected or diagnosed obstruction and/or ongoing pain.
- Complicating urinary tract sepsis.
- Recurrent calculi.
Standard Treatment Guidelines and Essential Medicines List for South Africa, Adult Hospital Level, 2020-2024_Version 1.0_17 October 2024
Chapter 7 Nephrology/Urological Disorders_7.3 Urological Disorders_7.3.8 Renal Calculi