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Respiratory Conditions

Standard Treatment Guidelines and Essential Medicines List for South Africa, Hospital Level, Adults 2019 Edition

Dyspnoea

Respiratory secretions


For Coronavirus Disease-19. See PHC Infections and related conditions: COVID-19: CORONAVIRUS DISEASE-19.


DYSPNOEA

R06.0+ (Z51.5)

DESCRIPTION

  • Dyspnoea is the subjective unpleasant sensation of being unable to breathe adequately (breathlessness). 
  • Dyspnoea is a complex multidimensional symptom with physical, psychological, and emotional dimensions, especially anxiety.
  • The intensity of dyspnoea is generally not related to the oxygen saturation.
  • Look for reversible causes, e.g. infection, pulmonary embolism, pleural effusion, bronchospasm and anxiety.
  • The aim should always be to address the cause. However, in end stage disease, symptomatic treatment is indicated.

GENERAL MEASURES

  • Ideally, include a physiotherapist and occupational therapist for pulmonary rehabilitation and to teach patients pursed lip breathing, pacing of activities, relaxation techniques, and positioning.
  • The use of a fan may reduce the sensation of dyspnoea.
  • Treat the underlying cause (e.g. antibiotics for underlying respiratory infection) wherever possible.

MEDICINE TREATMENT

  • Morphine syrup, oral.
    • Starting dose: 2.5-5 mg, 4 hourly as required, titrating up slowly.
    • In renal failure: start at 1-2 mg and observe patient closely before titrating up as required.

Dyspnoea associated with hypoxaemia

  • Oxygen.

RESPIRATORY SECRETIONS

R06.0 + (Z51.5)

DESCRIPTION

  • Excessive respiratory tract secretions (also referred to as death rattle), is used to describe a rattling noise produced by accumulated secretions in the airway which oscillate in time with inspiration and expiration.
  • Generally, respiratory secretions occur in patients who are extremely weak and close to death.

GENERAL MEASURES

  • Change position of the patient.
  • Explain to caregivers and relatives that the patient is not distressed by the secretion. Patients are not conscious that they are unable to clear secretions.
  • Minimal oropharyngeal suctioning is required.

MEDICINE TREATMENT

  • Hyoscine butylbromide, SC/IM, 20 mg.
    • Increase dose to effect to maximum of 120 mg. 

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Standard Treatment Guidelines and Essential Medicines List for South Africa, Adult Hospital Level, 2020-2024_Version 1.0_07 November 2024

Chapter 24: Medicines used in Palliative Care_24.4 Respiratory Conditions

Drugs mentioned

ICD-10 codes

NeoHealth® ID 20086 · updated 7/11/2025