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Shock

Description General measures Medicine treatment Fluid therapy for shock Vasoactive medicines for shock ICD-10 code: R57 Description Shock is defined as a state where perfusion is inadequate to meet the metabolic needs at a cellular level. There are various forms of shock each requiring their own specific treatment. LoE: IVb iii General Measures The therapeutic aim for all types of shock is to res

Description

General measures

Medicine treatment

Fluid therapy for shock

Vasoactive medicines for shock


ICD-10 code: R57

Description

Shock is defined as a state where perfusion is inadequate to meet the metabolic needs at a cellular level. There are various forms of shock each requiring their own specific treatment.

LoE: IVbiii

General Measures

The therapeutic aim for all types of shock is to restore perfusion and maintain an adequate blood pressure, e.g. Mean Arterial Pressure (MAP) >65mmHg.

Management includes fluid therapy and administration of vasoactive medication that may vary depending on the type of shock (See Shock):

For hypovolaemic shock: see Hypovolaemic shock.
For distributive shock: see Distributive shock.
For anaphylactic shock: see Anaphylaxis/ anaphylactic shock.
For neurogenic shock: see Neurogenic shock.
For septic shock: see Septic shock and Sepsis in ICU.
For cardiogenic shock: see Cardiogenic shock.
For obstructive shock: see Obstructive shock.

Medicine Treatment

Fluid therapy

Balanced salt solutions are the preferred resuscitation fluids for shock. Adequacy of fluid resuscitation should be guided by measures of fluid responsiveness.

LoE: IIIbiv


CAUTION
Avoid colloids for shock resuscitation in patients with sepsis and acute kidney injury.


LoE: IIIbv

Vasoactive therapy

Vasoactive therapy is indicated in a shocked patient that fails to respond to fluid therapy.

  • Adrenaline, IV, 0.01-1.0 mcg/kg/min as a continuous infusion.
    • Aim to achieve a target MAP >65mmHg within 30 minutes.

LoE: IVbvi

If shock is suspected to be cardiogenic in origin:

  • Dobutamine, IV, 5-20 mcg/kg/min as a continuous infusion.

LoE: IVbvii

Fluid Therapy for shock

Description

  • Balanced salt solutions are the preferred resuscitation fluids for shock.
  • Adequacy of fluid resuscitation should be guided by measures of fluid responsiveness.

LoE: IIIbviii


CAUTION
Avoid colloids for shock resuscitation in patients with sepsis and acute kidney injury.


LoE: IIIbix

Vasoactive medicines for shock

Description

Vasoactive therapy is indicated in a shocked patient that fails to respond to fluid therapy.

Medicine Treatment

  • Adrenaline, IV, 0.01-1.0 mcg/kg/min as a continuous infusion.
    • Aim to achieve a target MAP >65mmHg within 30 minutes.

LoE: IVbx

If shock is suspected to be cardiogenic in origin:

  • Dobutamine, IV, 5-20 mcg/kg/min as a continuous infusion.

LoE: IVbxi

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Standard Treatment Guidelines and Essential Medicines List for South Africa Adult Hospital _Chapter 23: Adult Critical Care_NEMLC Medicine Recommendations Review Cycle_ 2020_2023

Drugs mentioned

NeoHealth® ID 36428 · updated 7/3/2024