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Status Epilepticus

Status Epilepticus

Definition: 

Convulsion lasting 30 minutes or more – may be continuous or child may flit in and out of seizure. Failure to regain consciousness needs to be regarded as part of status. (Seizures that reoccur without recovery of full consciousness in between).After30minutesof generalized tonic-clonic seizures, the brain will suffer from hypoxia, acidosis, depletion of local energy stores, cerebral oedema and structural damage. Convulsions that last for 5 minutes or more, should be managed as for Status. 

Management of status epilepticus: Click here to see Flowchart.


Remember Airway, Breathing, Circulation first. 

Check HGT immediately, as hypoglycemic seizures can cause severe brain damage and does not respond well to anticonvulsants. 

There are many options to treat seizures. 


Use the available route and most appropriate drug that is available. 

Acute Antiepileptic Drug Doses: See algorithm under emergencies section.

Lorazepam 
0,1 mg/kg IV
1-2 mg buccal 
Diazepam
0,1-0,2 mg/kg IV 
0,5 mg/kg PR 
Midazolam 
0,1-0,2 mg/kg IV / IM
1-4mcg/kg/min infusion
0,5 mg/kg buccal
Phenobarbitone
20 mg/kg IV then 10mg/kg x 2 
Can be given IM
Phenytoin 
15-20mg/kg slowly over 30min



Drugs mentioned

NeoHealth® ID 20765 · updated 9/15/2021