TB Control Programme: Medicine Regimens in Adults

A15.0-3/A15.7-8/A16.0-2/ A16.4/A16.7-8 + (B20.0)

Treatment should be given once daily, seven days per week, in both the intensive and continuation phases.

• R – Rifampicin
• H – Isoniazid
• Z or PZA– Pyrazinamide
• E or EMB – Ethambutol

Pre-treatment body weight  kg	Two months initial phase	Four months continuation phase
	RHZE (150/75/400/275)	RH (150/75)	RH  (300/150)
30–37 kg	2 tablets	2 tablets	-
38–54 kg	3 tablets	3 tablets
55–70 kg	4 tablets	-	2 tablets
≥71 kg	5 tablets		2 tablets

• Adhere to the correct dose and the duration of treatment
• Weigh patient frequently and adjust the dose according to current weight

Click here to access the pdf.

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Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare, 2020-4-Version 1.0_16 September 2024

Chapter 17: Respiratory Conditions_17.4 Pulmonary Tuberculosis (TB)_17.4.1 Pulmonary Tuberculosis (TB) in Adults_17.4.1.2 TB control programme: medicine regimens in adults