GuidelinesIMCI
TB Treatment (Age 2 months up to 5 years)
IMCI - Child (Age 2 months up to 5 years)
Teach the Caregiver to Give Oral Medicines at Home
- Follow the general instructions for all oral medicines to be given at home
- Also follow the instructions listed with the dosage table of each medicine
- Do not change the regimen of children referred from hospital or a TB clinic without discussing this with an expert
- Treatment should be given as Directly Observed Treatment (DOT) 7 days a week
- Follow-up children each month to check adherence and progress
Give Regimen 3A for Uncomplicated TB
- Uncomplicated TB includes low bacilliary load TB disease such as pulmonary TB with minimal lung parenchymal involvement (with or without involvement of hilar nodes), TB lymphadenitis and TB pleural effusion
- All children should receive Rifampicin/INH (RH) together with pyrazinamide (PZA) for two months followed by RH for a further four months
- For small infants dissolve one dispersible PZA tablet (150 mg) in 3 ml of water
- Add Pyridoxine 12.5mg daily for 6 months if the child is HIV positive or malnourished
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Regimen 3A
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Intensive phase two months
Once daily
RH (60mg/60)mg, PZA (500mg) OR PZA 150 mg/3 ml |
Continuation phase four months Once daily
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Weight
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RH (60 mg/60)mg
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PZA (500 mg)
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PZA 150 mg/3 ml
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RH (60 mg/60mg)
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2 - < 3 kg
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1/2 tab
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Expert advice on dose
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1.5 ml
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1/2 tab
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3 - < 4 kg
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3/4 tab
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1/4 tab
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2.5 ml
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3/4 tab
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4 - < 6 kg
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1 tab
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1/4 tab
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3 ml
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1 tab
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6 - < 8 kg
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1½ tab
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1/2 tab
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1½ tabs
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8 - < 12 kg
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2 tabs
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1/2 tab
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2 tabs
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12 - < 15 kg
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3 tabs
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1 tab
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3 tabs
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15 - < 20 kg
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3½ tabs
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1 tab
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3½ tabs
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20 - < 25 kg
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4½ tabs
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1½ tabs
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4½ tabs
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25- < 30 kg
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5 tabs
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2 tabs
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5 tabs
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Give Regimen 3B for Complicated TB
- Use this regimen in children with all forms of severe TB (extensive pulmonary TB, spinal or osteo-articular TB or abdominal TB) or retreatment cases
- All children should receive four medicines during the intensive phase (Rifampicin/INH (RH),pyrazinamide (PZA) and ethambutol) for two months. This is followed by RH for a further four months (continuation phase)
- For small infants dissolve one dispersible PZA tablet (150 mg) in 3 ml of water
- To make ethambutol solution, crush one tablet (400 mg) to a fine powder and dissolve in 8ml of water. Discard unused solution
- Add Pyridoxine 12.5 mg daily for 6 months if the child is HIV positive or malnourished

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Integrated Management of Childhood Illness 2022; Child (Age 2 months up to 5 years); Oral Medicines; TB Treatment
Last checked for updates: June 2023