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GuidelinesIMCI

TB Treatment (Age 2 months up to 5 years)

IMCI - Child (Age 2 months up to 5 years)

Teach the Caregiver to Give Oral Medicines at Home

  • Follow the general instructions for all oral medicines to be given at home
  • Also follow the instructions listed with the dosage table of each medicine
  • Do not change the regimen of children referred from hospital or a TB clinic without discussing this with an expert
  • Treatment should be given as Directly Observed Treatment (DOT) 7 days a week
  • Follow-up children each month  to check adherence and progress

Give Regimen 3A for Uncomplicated TB

  • Uncomplicated TB includes low bacilliary load TB disease such as pulmonary TB with minimal lung parenchymal involvement (with or without involvement of hilar nodes), TB lymphadenitis and TB pleural effusion
  • All children should receive Rifampicin/INH (RH) together with pyrazinamide (PZA) for two months followed by RH for a further four months
  • For small infants dissolve one dispersible PZA tablet (150 mg) in 3 ml of water
  • Add Pyridoxine 12.5mg daily for 6 months if the child is HIV positive or malnourished
Regimen 3A
Intensive phase two months 
Once daily
RH (60mg/60)mg, PZA (500mg) OR PZA 150 mg/3 ml
Continuation phase four months Once daily
Weight
RH (60 mg/60)mg
PZA (500 mg)
PZA 150 mg/3 ml
RH (60 mg/60mg)
2 - < 3 kg
1/2 tab
Expert advice on dose
1.5 ml
1/2 tab
3 - < 4 kg
3/4 tab
1/4 tab
2.5 ml
3/4 tab
4 - < 6 kg
1 tab
 1/4 tab
3 ml
1 tab
6 - < 8 kg
1½ tab
 1/2 tab
 
1½ tabs
8 - < 12 kg
2 tabs
1/2 tab
 
 2 tabs
12 - < 15 kg
3 tabs
1 tab
 
3 tabs
15 - < 20 kg
3½ tabs
1 tab
 
3½ tabs
20 - < 25 kg
4½ tabs
1½ tabs
 
4½ tabs
25- < 30 kg
5 tabs
2 tabs
 
5 tabs

Give Regimen 3B for Complicated TB

  • Use this regimen in children with all forms of severe TB (extensive pulmonary TB, spinal or osteo-articular TB or abdominal TB) or retreatment cases
  • All children should receive four medicines during the intensive phase (Rifampicin/INH (RH),pyrazinamide (PZA) and ethambutol) for two months. This is followed by RH for a further four months (continuation phase)
  • For small infants dissolve one dispersible PZA tablet (150 mg) in 3 ml of water
  • To make ethambutol solution, crush one tablet (400 mg) to a fine powder and dissolve in 8ml of water. Discard unused solution
  • Add Pyridoxine 12.5 mg daily for 6 months if the child is HIV positive or malnourished

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Integrated Management of Childhood Illness 2022; Child (Age 2 months up to 5 years); Oral Medicines; TB Treatment


Last checked for updates: June 2023 

 

Drugs mentioned

NeoHealth® ID 17156 · updated 8/18/2023