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Tetanus Prophylaxis

Tetanus Prophylaxis

PART A - Algorithm

PART B - Introduction and Description


IF THE PATIENT ALREADY CLINICALLY HAS TETANUS, THIS IS A NOTIFIABLE CONDITION.

ICD9
ICD10
Medical Condition
037
A35
Tetanus (ICD10: other)
7713
A33
Tetanus neonatorum


Contacts details for NOTIFICATION: 

Western Cape

Information Management Directorate

23rd Floor, Room 7, 4 Dorp Street, Cape Town

Tel: 021 483 4661

Fax: 021 483 3277



Part A - Algorithm


Part B

Introduction/Description

This guideline describes prophylaxis for tetanus and not management of the developed disease. IF THE PATIENT ALREADY CLINICALLY HAS TETANUS, THIS IS A NOTIFIABLE CONDITION.

  • Tetanus is a toxin-mediated disease, caused by Clostridium Tetani and characterized by severe uncontrolled skeletal muscle spasms
  • Involvement of respiratory muscles leads to hypoventilation, hypoxia and death
  • Infection occurs through wound contamination
  • Tetanus symptoms are delayed: Do not delay Vaccination if you suspect a high risk wound

Diagnosis of problem and differential diagnosis

Any patient with an open wound or burns should be evaluated for tetanus vaccination status and tetanus risk exposure and vaccinated as required.

The South African Vaccination schedule for Tetanus Prophylaxis is:

  1. 6 weeks (DTP)
  2. 10 weeks (DTP)
  3. 14 weeks (DTP)
  4. 18 months (DTP)
  5.  5 years (DTP)

Booster every 10 years

TRIAGE patient using SATS: Triage status will depend on the extent of the injuries.

Categorise the wound according to EXPOSURE RISK
CATEGORY 1
CATEGORY 2
CATEGORY 3
Clean wound
Tetanus Prone Wound
High Risk Wound
Any Clean Cut
Wounds or Burns requiring surgical debridement with a delay of > 6 hrs
Wounds or Burns requiring surgical debridement with a significant amount of devitalised tissue
Wound obviously contaminated with soil, rust or manure
Wound containing foreign material
Compound Fractures

Heavy Contamination
IV Drug users
Immunocompromised patients


Management (based on severity)

Wound Management

  • Clean the wound
  • Flush well with soap and water or water alone for 5 minutes
  • Apply disinfectant (70% alcohol or iodine solution)
  • Debride dirty wounds - surgical debridement may be needed
  • Suture clean wounds <6 hrs old
  • If >6 hrs old consider secondary closure after debridement
  • Give antibiotics only if wound already infected

Immunisation



Fully Immunised
5 doses AND Booster < 10 yrs ago

Primary Immunisation
Complete BUT Booster
> 10 yrs ago

Not Immunised
OR Status Unknown
OR Uncertain

Category 1
Clean Wound

No booster required
Give booster
Give booster
Refer to clinic for completion of course

Category 2
Tetanus Prone Wound

No booster required
Give booster
Give booster
Refer to clinic for completion of course

Category 3
High Risk Wound

No booster required
GIVE Human Tetanus Immunoglobulin

Give booster
Refer to clinic for completion of course
AND
Human Tetanus Immunoglobulin

Give booster
Refer to clinic for completion of course
AND
Human Tetanus Immunoglobulin


Dose chart

  • Booster Vaccination = Tetanus Toxoid 0.5 mg IM
  • Human Tetanus Immunoglobulin (Ig)
  • Dose = 250 IU IM
  • Unless
  • > 24 hrs old
  • Burns
  • Heavy Contamination
  • Then give 500 IU IM
  • Give at site different from Immunisation

History

  • DMIST Handover from Ambulance
  • SAMPLE HISTORY
  • Signs and Symptoms
  • Allergies
  • Medications
  • Past Medical history
  • Last Meal
  • Events

Examination

  • Assess ABC’s, injuries and the wound
  • Measure and Record Vital Signs

Investigations

Depend on the clinical scenario

Referral Criteria (L1/2/3)

  • Admit for injuries requiring inpatient intervention

Discharge and Admission Criteria/Checklist

  • Follow up, suture removal and wound care should be done at clinic level.

Emergency Centre Wound Care Advice

  • Keep the wound clean and dry for at least 5 days. If you get it wet, dab it dry with some clean tissue. If there is a dressing over the wound, remove it and gently pat the wound dry leaving glue or steri-strips in place.
    • Don’t pick or put your fingers in the wound whilst it is healing as this can cause infection.
  • Steri-strips: Stay in place for 5-7 days unless you are advised differently. Go to the clinic to remove them and have the wound checked. If the ends of the steri-strips peel back, trim them with scissors to stop them catching and being pulled off.
  • Glue:  will drop off by itself when the wound is healed. This usually takes 5 days.
  • Stitches: Keep stitches clean and dry. The doctor/nurse will tell you how long they have to stay in for. Go to the clinic to get the stitches removes and the wound checked.
  • If the wound becomes more painful, despite taking painkillers, red, hot and swollen or if pus comes out of the wound you need to go to your clinic
    • If your dressing becomes very dirty or blood stained, go to your clinic for a clean dressing.

References

  • Rosens Emergency Medicine 7th edition.
  • Tintinallis 4th ed.

Drugs mentioned

ICD-10 codes

NeoHealth® ID 18592 · updated 9/15/2021