Toxoplasmosis
Description Medicine Treatment Referral B58 + (B20.8) DESCRIPTION Initial diagnosis can only be made at hospital level. MEDICINE TREATMENT Cotrimoxazole, oral, 320/1600 mg 12 hourly for 4 weeks. Then 160/800 mg 12 hourly for 12 weeks. Secondary prophylaxis Cotrimoxazole, oral 160/800 mg daily. Continue until the CD4 count has risen to >200 cells/mm 3 on ART. Commence ART. REFERRAL
B58 + (B20.8)
DESCRIPTION
Initial diagnosis can only be made at hospital level.
MEDICINE TREATMENT
- Cotrimoxazole, oral, 320/1600 mg 12 hourly for 4 weeks.
- Then 160/800 mg 12 hourly for 12 weeks.
Secondary prophylaxis
- Cotrimoxazole, oral 160/800 mg daily.
- Continue until the CD4 count has risen to >200 cells/mm3 on ART.
- Commence ART.
REFERRAL
Patients with suspected toxoplasmosis infection requiring further investigation to confirm diagnosis.
Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare_V1.0_26 February 2026
Chapter 11: Human Immunodeficiency Virus and Acquired Immune Deficiency Syndrome (HIV AND AIDS)_11.3 Opportunistic Infections, Treatment in Adult_11.3.15 Toxoplasmosis