Treatment Of Children Who Were Previously Successfully Treated For TB (Retreatment)
A child who was previously successfully treated for pulmonary TB is at increased risk for re-infection with TB. It is imperative to exclude drug-resistant TB by carrying out a sputum rapid TB molecular test (e.g. GeneXpert®) plus culture with drug susceptibility testing (DST), and also determine DST of any known TB source case. If the above does not indicate resistant TB, treat as drug susceptibl
A child who was previously successfully treated for pulmonary TB is at increased risk for re-infection with TB. It is imperative to exclude drug-resistant TB by carrying out a sputum rapid TB molecular test (e.g. GeneXpert®) plus culture with drug susceptibility testing (DST), and also determine DST of any known TB source case. If the above does not indicate resistant TB, treat as drug susceptible TB (high bacillary load) with close monitoring of response. Consider an extension of the duration of the continuation phase of therapy in these retreatment cases.
REFERRAL
- Poor clinical response to TB retreatment.
Standard Treatment Guidelines And Essential Medicines List For South Africa, Hospital Level, Paediatrics, 2023 Edition
Chapter 10: Tuberculosis, 10.6 Treatment Of Children Who Were Previously Successfully Treated For TB (Retreatment)