GuidelinesPrimary Care STG
Treatment of More than One STI Syndrome
Sexually Transmitted Infections
STI syndromes | Treatment (New episode) |
| MUS + SSW | Treat according to SSW flow chart |
| MUS + BAL | Treat according to MUS flow chart AND - Clotrimazole cream, 12 hourly for 7 days |
| MUS + GUS | - Ceftriaxone, IM, 250 mg immediately as a single dose AND - Azithromycin, oral, 1 g as a single dose AND - Aciclovir, oral, 400 mg 8 hourly for 7 days* |
| VDS + LAP | Treat according to LAP flow chart AND Treat for candidiasis, if required (see VDS flow chart) |
| VDS + GUS | - Ceftriaxone, IM, 250 mg immediately as a single dose AND - Metronidazole, oral, 2 g immediately as a single dose AND - Azithromycin, oral, 1 g as a single dose AND - Aciclovir, oral, 400 mg 8 hourly for 7 days* AND Treat for candidiasis, if required (see VDS flow chart) |
| LAP + GUS | Ceftriaxone, IM, 250 mg immediately as a single dose AND Metronidazole, oral, 400 mg 12 hourly for 7 days AND Aciclovir, oral, 400 mg, 8 hourly for 7 days* AND Azithromycin, oral, 1 g as a single dose |
| SSW + GUS | Ceftriaxone, IM, 250 mg immediately as a single dose AND Aciclovir, oral, 400 mg 8 hourly for 7 days* AND Azithromycin, oral, 1 g as a single dose |
*Treat with aciclovir only if HIV status is positive or unknown **Penicillin allergic men and non-pregnant women avoid ceftriaxone and refer to relevant algorithms Penicillin allergic pregnant/ breastfeeding women, refer for penicillin desensitisation | |
Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare Level, 2020 Edition