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Vaginal Discharge (PVD)

Infection Vaginal Discharge (PVD) Brief outline/clinical setting PVD does not necessarily mean there is PID or bacterial vaginosis. Detailed history and clinical examination is warranted to exclude sinister causes of PVD like Ca Cervix. If infective cause-ALWAYS treat partner/s All PVD in prepubertal girls and children (below age of consent) to be discussed with an ED-CONSULTANT and REFERRED to G

Infection Vaginal Discharge (PVD)
Brief outline/clinical setting PVD does not necessarily mean there is PID or bacterial vaginosis. Detailed history and clinical examination is warranted to exclude sinister causes of PVD like Ca Cervix.
If infective cause-ALWAYS treat partner/s
All PVD in prepubertal girls and children (below age of consent) to be discussed with an ED-CONSULTANT and REFERRED to GYNAE ON CALL.
Aetiologies/organisms

Vaginal candidiasis

  • Caused by Candida albicans/ glabrata/ cerviciensis
  • Clotrimazole long-acting pessary (Canesten ‘1’) single dose
  • Alternatives clotrimazole, econazole (Pevaryl) or miconazole (Daktarin) vaginal creams, applied daily before bedtime for 7 days

Trichomoniasis

  • profuse offensive discharge
  • classical ‘strawberry cervix’ on speculum and Frothy greyish discharge
  • Metronidazole 2 g orally as a single dose, or 400 mg orally twice daily for 7 days.

Bacterial vaginosis

  • represents overgrowth of the vagina with bacteria- mainly anaerobic bacteria
  • complaint may be of a fishy smelling vagina
  • Metronidazole 2 g orally as a single dose, or 400 mg orally twice daily for 7 days OR
  • Clindamycin 300mg bd po for 7 days.
  • Recurrence-refer GOPD

Mucopurulent cervicitis and gonococcal cervicitis

  • Gonorrhoea or Chlamydia cause cervicitis
  • The discharge is yellowish and non-offensive
  • Ceftriaxone 1g daily im as a single dose for gonorrhoea plus either
  • Azithromycin 1G as a stat dose or
  • Doxycycline 100 mg orally twice daily for 10 days (which will also cover chlamydia)
  • Metronidazole 400 mg orally twice daily for 10 days may be added

Pelvic inflammatory disease
Cervical or endometrial malignancy

  • A blood stained and foul-smelling discharge may be caused by malignancy.
  • A speculum examination is always mandatory.
  • Any suspicious lesion seen to be discussed with Gynae Team On-Call
  • Consider cervical biopsy, endometrial biopsy and/or transvaginal ultrasound for women over the age of 45 years.

Cervical ectropion

  • called a ‘cervical erosion’
  • The cervix looks reddened at the centre since the mucus-producing epithelium of the endocervix is exposed at the external os
  • Complaint is of a profuse in-offensive clear or cloudy discharge
  • Do not confuse with cancer
  • Discuss cases with a consultant to avoid missing a malignancy – seek Gynae review

Physiological vaginal discharge

  • Normal discharge varies between individuals, within individuals, with the menstrual cycle and with pregnancy
  • The discharge is whitish and is not fishy or foul-smelling
  • If in doubt about infection, prescribe:
  • Doxycycline 100 mg orally twice daily and
  • Metronidazole 400 mg orally three times daily for 10 days
  • Note this may not always be helpful

Foreign Body

  • usually presents with a foul-smelling or blood-stained vaginal discharge
  • Broad spectrum antibiotics if necessary, e.g. amoxicillin 500 mg orally 3 times daily, with metronidazole 400 mg orally 3 times daily
  • Vaginal oestrogen cream for a child less than 8 years old
Duration Varies dependent on cause as above
Alternative if allergic/not available Seek Gynae consultation
Rationale
  
Level of evidence  

Link to Guideline Click here

CMJAH Antimicrobial Therapy Guideline - Community Acquired Infections Adult Emergency Department 2020

Drugs mentioned

NeoHealth® ID 23828 · updated 11/30/2021