Neobook — clinical reference

Infection	Vincent’s angina
Brief outline/clinical setting	Vincent’s angina refers to acute necrotizing ulcerative lesions of the oral mucosal membranes and tonsils, with bleeding inflammation and halitosis
Aetiologies/organisms	Organisms involved are polymycrobial but often include Fusobacterium necrophorum, Treponema, Selenomonas, Prevotella
Optimal antimicrobial selection	Amoxicillin 1g PO TID for 10d plus metronidazole 250 mg PO TDS or Amoxicillin-clavulanate 500 mg/125 mg PO TID or 875 mg/125 mg PO BD Chlorhexidine 0.12% oral rinse 15ml BD If patient is HIV positive, add nystatin oral rinse 5ml QID or fluconazole 200mg PO daily for 7-14 days
Duration	10 days
Alternative if allergic/not available	Clindamycin 150-300 mg PO TDS for 10 days Or Doxycycline 100mg PO BD for 10 days
Rationale	Marx, J. A., Hockberger, R. S., Walls, R. M., & Adams, J. (2002). Rosen's emergency medicine: Concepts and clinical practice. St. Louis: Mosb
Level of evidence
Link to Guideline

Vincent’s Angina