Vitamin B6/pyridoxine deficiency *New*
ICD-10 code: E53.1 Description General measures Medicine treatment Referral DESCRIPTION Commonly presents as signs of peripheral neuropathy including: tingling sensation. burning pain or numbness of the feet. Pyridoxine deficiency is related to: malnutrition. alcoholism. isoniazid or combination TB therapy. GENERAL MEASURES Dietary advice: Increase intake of pyridoxine rich foods such as: Liver,
ICD-10 code: E53.1
Description
General measures
Medicine treatment
Referral
DESCRIPTION
Commonly presents as signs of peripheral neuropathy including:
- tingling sensation.
- burning pain or numbness of the feet.
Pyridoxine deficiency is related to:
- malnutrition.
- alcoholism.
- isoniazid or combination TB therapy.
GENERAL MEASURES
Dietary advice: Increase intake of pyridoxine rich foods such as:
- Liver, meat, fish and offal,
- Wholegrain cereals, fortified breakfast cereals,
- Peanuts, bananas, raw vegetables,
- Walnuts and seeds, avocados, dried fruits,
- Potatoes and baked beans.
MEDICINE TREATMENT
For deficiency
Children
- Pyridoxine, oral, 12.5 mg daily for 3 weeks.
Adults
- Pyridoxine, oral, 25 mg daily for 3 weeks.
For medicine-induced neuropathy
Children
- Pyridoxine, oral, daily for 6 months.
- < 5 years of age: 12.5 mg daily.
- ≥ 5 years of age: 25 mg daily.
Adults
- Pyridoxine, oral, 200 mg daily for 3 weeks.
Then follow with:
- Pyridoxine, oral, 25 mg daily as maintenance dose (for patients on TB therapy/isoniazid).
REFERRAL
Failure to respond.
Children.
Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare Level, Updated for the 2023 Edition