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Wound Infections/ Surgical Site Infections (SSI)

Infection Wound Infections / Surgical site infections (SSI) Brief outline/clinical setting Accounts for 20% of all hospital-acquired infections. Divided into the categories of - superficial incisional SSI (skin or subcutaneous tissue), - deep incisional SSI (fascia or muscular layers), and - organ/space SSI (any part of the body opened or manipulated during a procedure, excluding the previously m

Infection Wound Infections / Surgical site infections (SSI)
Brief outline/clinical setting

Accounts for 20% of all hospital-acquired infections.
Divided into the categories of
- superficial incisional SSI (skin or subcutaneous tissue),
- deep incisional SSI (fascia or muscular layers), and
- organ/space SSI (any part of the body opened or manipulated during a procedure, excluding the previously mentioned layers)

Local signs of pain, swelling, erythema, and purulent drainage provide the most reliable information in diagnosing an SSI.

Aetiologies/organisms S. aureus, Streptococci spp, Enterobacterales, Enterococci spp, P. aeruginosa, A. baumannii, anaerobes, Candida spp
Optimal antimicrobial selection Please consult microbiology for specific empiric antimicrobial selection, based on unit specific epidemiology, and directed therapy based on culture results.
Rationale The most important therapy for an SSI is to open the incision, evacuate the infected material, and continue dressing changes until the wound heals by secondary intention
Level of evidence RCT
Link to Guideline Click here
NeoHealth® ID 23862 · updated 3/27/2024