Articles
Desmopressin for nocturnal enuresis in children
A review of 95 studies on bedwetting found that desmopressin may reduce the frequency of wet nights compared to a placebo. Its effectiveness is similar to alarm therapy, although alarm therapy shows more sustained long-term success. Combining desmopressin with alarm therapy or anticholinergics may be slightly more effective than desmopressin alone. The overall evidence quality remains low or very low.
Enuresis (bedwetting) affects up to 20% of five‐year‐old children and 2% of adults. Although spontaneous remission often occurs, the social, emotional and psychological costs can be great. Desmopressin has been used to treat bedwetting since the 1970s.
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