Mometasone Furoate
Indications
Registered South African indications:
- Asthma
Cautions
Contraindications
- Hypersensitivity to the active ingredient or any of its excipients
- Pregnancy
- Lactation
Cautions
- Renal impairment
- Hepatic impairment
- Milk protein allergy
- Adrenal suppression
- Immunosuppression
- History of psychiatric disorder
- Hypothalamic-pituitary adrenal axis suppression
- Untreated systemic infection
- Ocular herpes simplex
- Previous oral steroid use
- Physiological stress
Adult dosage
Forms avail. in SA and covered in this monograph: inh
Chronic asthma - Mild to moderate
- Inhaled (inh): 200-400μg, 12-24hrly; Max: 400μg/24hrs
Chronic asthma - Severe
- Inhaled (inh): 400μg, 12hrly; Max: 800μg/24hrs
Paediatric dosage
Not established for use in children below 12 years
Special populations
Pregnancy
- Contraindicated
Breastfeeding
- Contraindicated
Renal Impairment
Hepatic Impairment
Elderly
Adverse reactions
Central Nervous System Disorders
- Headache
- Psychomotor hyperactivity
- Sleep disorders
- Anxiety
- Depression
- Aggression
Respiratory Disorders
- Acute asthma
- Pharyngitis
- Dysphonia
Immune, Blood and Lymphatic System Disorders
- Candidiasis
- Hypersensitivity reactions
Interactions
- CYP3A4 inhibitors1,2U2D
Monitoring
None routine
Prescribing points
Hazard
- Instruct patients not to smoke or go near naked flames - risk of severe burns
- Fabric (clothing, bedding, dressings, etc) that has been in contact with this product burns more easily and is a serious fire hazard
- Washing clothing and bedding may reduce product build-up but not totally remove it
Mechanism of action
Mometasone furoate is a glucocorticoid with anti-inflammatory properties. It is likely that its mechanism lies in its ability to inhibit the release of mediators of allergic reactions. Mometasone significantly inhibits the release of leukotrienes from leucocytes in allergic patients.
Dosage forms
- Inhaler
Formulation
Inhaler 200μg
- Asmanex ( Organon) originator
Inhaler 400μg
- Asmanex ( Organon) originator
Also available in the following forms: Nasal spray, cream, ointment and lotion.
COMBINATION PREPARATIONS
Mometasone furoate/Formoterol Fumarate dihydrate
Inhaler 100μg/5μg
- Dulera Inhaler (MSD) originator
Inhaler 200μg/5μg
- Dulera Inhaler (MSD) originator
References
1.https://www.medicines.org.uk/emc/medicine/11551 (04/12/2014_Merck_Asmanex _400mcg inh pwd) 2. https://www.medicines.org.uk/emc/medicine/24365 (04/12/2014_Merck_Asmanex_200mcg inh pwd) 3. https://drive.google.com/drive/folders/0B0xnChtF7vduQU5zTU9ZZmduMFU (14/08/2009_MSD_Asmanex_200, 400mcg inh) 4. SmPC: Elocon Cream, Merck Sharp & Dohme Limited; Last updated on eMC: 25 Jul 2019; Downloaded online: 11 Apr 2020 [https://www.medicines.org.uk/emc/product/78/smpc/print]
Brands & products
23 products · stale NAPPI snapshot · refreshed 5/29/2026 · 158 days oldsprayGeneric· 4 products
from R1.74/unit| Product | Strength | Pack | Sched | SEP | Unit | Disp fee | NAPPI |
|---|---|---|---|---|---|---|---|
| Mometasone Clicks Nasal Spray | 50 mcg | 120 | S2 | R208.65 | R1.74 | R82.61 | 3000396001 |
| Zilfone 120dose | 50 mcg | 120 | S2 | R208.66 | R1.74 | R82.61 | 724010001 |
| Trisone Ns | 50 µg | 140 | S2 | R286.27 | R2.04 | R103.96 | 3004673001 |
| Zomate Ns | 50 µg | 140 | S2 | R332.13 | R2.37 | R116.58 | 3004661001 |
AqsGeneric· 5 products
from R2.34/unit| Product | Strength | Pack | Sched | SEP | Unit | Disp fee | NAPPI |
|---|---|---|---|---|---|---|---|
| Nexomist 140 metered doses | 50 µg | 140 | S2 | R328.30 | R2.34 | R115.52 | 713968001 |
| Monact | 50 mcg | 140 | S2 | R346.32 | R2.47 | R120.48 | 3004007001 |
| Rinelon aqueous 140dose | 50 mcg | 140 | S2 | R397.91 | R2.84 | R134.67 | 883261007 |
| Rinelon 60 dose | 50 mcg | 60 | S2 | R190.65 | R3.18 | R77.84 | 716718001 |
| Nasonex aqueous 140dose | 50 mcg | 140 | S3 | R546.25 | R3.90 | R164.82 | 883253004 |
Aqueous Nasal SprayGeneric· 1 product
from R2.40/unit| Product | Strength | Pack | Sched | SEP | Unit | Disp fee | NAPPI |
|---|---|---|---|---|---|---|---|
| Mometasone Ns Kiara | - ml | 140 | S2 | R336.53 | R2.40 | R117.79 | 3006851001 |
inhalerGeneric· 6 products
from R2.70/unit| Product | Strength | Pack | Sched | SEP | Unit | Disp fee | NAPPI |
|---|---|---|---|---|---|---|---|
| Dulera 100/5ug 120 dose | 100 mcg | 120 | S4 | R324.05 | R2.70 | R114.35 | 722934001 |
| Dulera 200/5ug 120 dose | 200 mcg | 120 | S4 | R424.24 | R3.54 | R141.92 | 722933001 |
| Asmanex Twisthaler 200 Μg | 200 mcg | 60 | S3 | R498.61 | R8.31 | R157.81 | 717572001 |
| Asmanex Twisthaler 200 Μg | 200 mcg | 30 | S3 | R269.80 | R8.99 | R99.43 | 717571001 |
| Asmanex Twisthaler 400 Μg | 400 mcg | 60 | S3 | R624.78 | R10.41 | R176.38 | 717582001 |
| Asmanex Twisthaler 400 Μg | 400 mcg | 30 | S3 | R344.10 | R11.47 | R119.87 | 717581001 |
creamGeneric· 3 products
from R9.86/unit| Product | Strength | Pack | Sched | SEP | Unit | Disp fee | NAPPI |
|---|---|---|---|---|---|---|---|
| Elocon | 1 mg/g | 15 | S4 | R147.95 | R9.86 | R63.07 | 782017029 |
| Momate | 1 mg/g | 20 | S4 | R273.00 | R13.65 | R100.31 | 718942001 |
| Elocon | 1 mg/g | 20 | S4 | R349.12 | R17.46 | R121.25 | 782017002 |
CreamGeneric· 1 product
from R13.57/unit| Product | Strength | Pack | Sched | SEP | Unit | Disp fee | NAPPI |
|---|---|---|---|---|---|---|---|
| Mometagen 0,1 % | 1 mg | 20 | S4 | R271.44 | R13.57 | R99.88 | 714014001 |
ointmentGeneric· 2 products
from R14.27/unit| Product | Strength | Pack | Sched | SEP | Unit | Disp fee | NAPPI |
|---|---|---|---|---|---|---|---|
| Momate | 1 mg/g | 20 | S4 | R285.35 | R14.27 | R103.71 | 718307001 |
| Elocon | 1 mg/g | 20 | S4 | R369.82 | R18.49 | R126.95 | 782025005 |
lotionGeneric· 1 product
from R15.71/unit| Product | Strength | Pack | Sched | SEP | Unit | Disp fee | NAPPI |
|---|---|---|---|---|---|---|---|
| Elocon | 1 mg/g | 30 | S4 | R471.33 | R15.71 | R153.80 | 788791030 |
- Asmanex Twisthaler
- Nexomist
Medical aid coverage
data not yet integrated- Comprehensive Series—
- Executive Plan—
- KeyCare Series—
- Priority Series—
- Saver Series—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- BonClassic—
- BonComprehensive—
- BonEssential—
- BonFit Select—
- BonSave—
- BonStart—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- Beryl—
- Emerald—
- Onyx—
- Ruby—
- Sapphire—
- Tanzanite One—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- Aquarium Option—
- Efficiency Option—
- Marine Option—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.