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Cardiac Arrest, Adults

Description Covid-19 considerations General Measures Emergency Treatment Immediate Emergency Medicine Treatment Additional Guidance Referral ICD-10 code: I46.0/I46.9 Figure 21.1: Advanced cardiac arrest algorithm ( adapted with permission from the Resuscitation Council of South Africa ) Click on the image to enlarge. Figure 21.2: Advanced cardiac arrest algorithm - suspected respiratory communica

Description

Covid-19 considerations

General Measures

Emergency Treatment

Immediate Emergency Medicine Treatment

Additional Guidance

Referral


ICD-10 code: I46.0/I46.9

Click on the image to enlarge.
Figure 21.1: Advanced cardiac arrest algorithm (adapted with permission from the Resuscitation Council of South Africa)
Click on the image to enlarge.

Click on the image to enlarge

Figure 21.2: Advanced cardiac arrest algorithm - suspected respiratory communicable disease (adapted with permission from the Resuscitation Council of South Africa)
Click on the image to enlarge.

DESCRIPTION

Defined as the loss of a heart beat and loss of a palpable pulse, irrespective of the electrical activity captured on ECG tracing. Irreversible brain damage can occur within 2-4 minutes.

Clinical features include:

  • sudden loss of consciousness;
  • absent carotid pulse; and
  • loss of spontaneous respiration.

LoE:IVb1

COVID-19 CONSIDERATIONS

  • The infection risk that CPR poses to providers due to aerosolization of coronavirus particles is not negligible.
  • This potential risk should be weighed against the probability of achieving spontaneous return of circulation to inform the decision to initiate or stop CPR.
  • For in hospital cardiac arrest in patients with suspected COVID-19, CPR has been shown to not be beneficial unless an immediate reversible cause is suspected, e.g., dislodgement of ET tube, etc. and is therefore not recommended.
  • For out of hospital cardiac arrest in patients with suspected COVID-19, it is recommended to not start conventional CPR in unwitnessed cardiac arrest as it will likely not be beneficial.
  • Appropriate PPE should be worn by all staff before initiating CPR: FFP3 mask, visor, gloves and gown.

LoE:IIIb2

GENERAL MEASURES

  • Diagnose cardiac arrest rapidly.
  • Make a note of the time of starting resuscitation.
  • Document medication given and progress after the resuscitation.
  • Follow instructions as per the appropriate algorithm (Fig 21.1 or 21.2) and below.

EMERGENCY TREATMENT

Hazards, Hello, Help

  • Assess for any hazards and remove. Make use of personal protective equipment i.e. gloves, masks.
  • Speak to the patient. If they respond, turn into recovery position and continue management as directed by findings.
  • If no response, check for carotid pulse and breathing. Take no longer than 10 seconds.
  • Call for skilled help and an automated external defibrillator (AED) or defibrillator.

Cardiopulmonary resuscitation (CPR)

  • Place the patient on a firm flat surface and commence resuscitation immediately.
  • Initiate CAB (Circulation Airway Breathing) sequence of CPR.
  • Check the rhythm as soon as defibrillator or AED is available and defibrillate if a shockable rhythm is identified.

Circulation

  • If there is no pulse or you are not sure, start with 30 chest compressions at a rate of 100-120 compressions per minute, and a depth of +/-5 cm.
  • Allow full chest recoil between compressions.
  • Minimise interruptions during compressions.

Airway and Breathing

  • To open the airway, lift the chin forward with the fingers of the one hand and tilt the head backwards with other hand on the forehead. Do not do this where a neck injury is suspected (see below).
  • If there is no normal breathing, give 2 breaths with bag-valve-mask resuscitator and face mask.
  • The administered breaths must cause visible chest rise.
  • If not able to perform breaths, continue compressions (reposition head and insert correctly sized oropharyngeal airway and try again after 30 compressions).
  • If advanced airway is placed, administer 1 breath every 6 seconds without interrupting chest compressions. Avoid excessive ventilation.
  • Oxygenate with 100% oxygen.
  • Repeat the cycle of 30 compressions followed by 2 breaths (30:2) until the AED or defibrillator arrives.

Where neck injury is suspected:

  • Do not perform a chin lift or head tilt manoeuvre if a neck injury is suspected.
  • To open the airway, use a jaw thrust:
    • place your fingers behind the jaw on each side
    • lift the jaw upwards while opening the mouth with your thumbs “Jaw thrust”
  • Ideally use a 3rd person to provide in-line manual stabilisation of the neck

Initiate fluids, IV/IO access

  • Sodium chloride 0.9%, IV, 1000 mL

LoE:IIb3

AED/Defibrillator

Attach leads and analyse rhythm as soon as the defibrillator arrives:

If pulseless with shockable rhythm (ventricular fibrillation/tachycardia)

  • Defibrillate, as indicated per algorithm (1 shock).
  • Immediately resume CPR. Starting with chest compressions.
  • Continue CPR cycles of 30:2 for 2 minutes, then reassess for a pulse.
  • Administer adrenaline (epinephrine) as per algorithm and medicine treatment below.
  • Seek reversible cause of arrest.
  • Continue CPR until spontaneous breathing and/or pulse returns.

If pulseless and no respirations with non-shockable rhythm

  • Immediately resume CPR. Starting with chest compressions.
  • Continue CPR cycles of 30:2 for 2 minutes then reassess for a pulse.
  • Administer adrenaline as per algorithm.
  • Seek reversible cause of arrest.
  • Continue CPR until spontaneous breathing and/or pulse returns.

IMMEDIATE EMERGENCY MEDICINE TREATMENT

Adrenaline (epinephrine) is the mainstay of treatment. Give immediately, IV, IO, or endotracheal, when there is no response to initial resuscitation or defibrillation.

  • Adrenaline (epinephrine 1 mg), 1:1 000, 1 mL , IV immediately as a single dose.
    • Flush with 5–10 mL of sterile water or sodium chloride 0.9%.
    • Repeat every 3–5 minutes during resuscitation.

OR

  • Adrenaline (epinephrine 1 mg), intra-osseous (IO), 1:1 000, 1 mL, via IO line.

LoE:IVb4

ADDITIONAL GUIDANCE

Connect bag-valve-mask resuscitator to 100% oxygen at 10-15L/min flow.
Check glucose and treat hypoglycaemia.
Continue CPR until spontaneous breathing and/or heart beat returns.
Assess continuously (every 2 minutes) until the patient shows signs of recovery.

Termination of resuscitation:

  • The decision to stop CPR attempts depends on the specifics of the individual patient and should be based on clinical judgement.
  • Consider stopping resuscitation attempts and pronouncing death if there is incurable underlying disease, or if asystole > 20 minutes or in the absence of the factors for prolonging resuscitation as listed below.

LoE:IIIb5

Consider carrying on for longer especially with:

  • hypothermia and drowning
  • poisoning or medicine overdose
  • neurotoxic envenomation (e.g. black and green mamba or Cape cobra snakebite) – see: Snakebites

This decision should take into consideration the potential risk that CPR poses to the rescuer e.g. infectious diseases.

REFERRAL

All patients: transfer with supportive care and accompanying skilled worker until care is taken over by doctor at receiving institution.

Click here for the pdf.

Click here for the NEMLC Recommendations for medicine amendments (2020-4 review cycle).


Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare, 2020-4_Version 1.1_October 2024

Chapter 21: Emergencies and Injuries

Drugs mentioned

ICD-10 codes

NeoHealth® ID 19782 · updated 3/13/2025