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Cardiac Arrest in Adults

Description Covid-19 considerations Emergency treatment Additional guidance ICD-10 code: I46.0/I46.9 DESCRIPTION   Described as the loss of a heart beat and a palpable pulse, irrespective of the electrical activity captured on ECG tracing. Irreversible brain damage can occur within 2–4 minutes. Clinical features include: sudden loss of consciousness absent carotid and all other pulses loss o

Description

Covid-19 considerations

Emergency treatment

Additional guidance


ICD-10 code: I46.0/I46.9

DESCRIPTION 

Described as the loss of a heart beat and a palpable pulse, irrespective of the electrical activity captured on ECG tracing. Irreversible brain damage can occur within 2–4 minutes.

Clinical features include:

  • sudden loss of consciousness absent carotid and all other pulses
  • loss of spontaneous respiration

LoE: IVbi

COVID-19 CONSIDERATIONS

  • The infection risk that CPR poses to providers due to aerosolization of coronavirus particles is not negligible.
  • This potential risk should be weighed against the probability of achieving spontaneous return of circulation to inform the decision to initiate or stop CPR.
  • For in-hospital cardiac arrest in patients with suspected COVID-19, CPR has been shown to not be beneficial unless an immediate reversible cause is suspected, e.g., dislodgement of ET tube, etc. and is therefore not recommended.
  • For out of hospital cardiac arrest in patients with suspected COVID-19, it is recommended to not start conventional CPR in unwitnessed cardiac arrest as it will likely not be beneficial.
  • Appropriate PPE should be worn by all staff before initiating CPR: FFP3 mask, visor, gloves and gown.

LoE: IIIbii

EMERGENCY TREATMENT

  • Diagnose rapidly. After ensuring the safety of the scene, commence resuscitation as per the appropriate acute adult cardiac arrest algorithm – Fig 20.1 or 20.2 above.
  • Make a note of the time of starting resuscitation.
  • Place the patient on a firm flat surface and commence resuscitation immediately.
  • Call for skilled help and an automated external defibrillator (AED) or defibrillator.
  • Initiate CAB (Circulation Airway Breathing) sequence of CPR (cardiopulmonary resuscitation).
  • Check the rhythm as soon as defibrillator or AED is available and defibrillate if a shockable rhythm is identified.
  • Document medication and progress after the resuscitation.

Cardiopulmonary resuscitation (CPR)

Circulation

  • Check for carotid pulse for about 5 seconds.
  • If there is no pulse or you are not sure, start with chest compressions at a rate of 100-120 compressions per minute to a depth of +/- 5cm. Push hard and allow full recoil of chest with minimum interruptions.

Airway and breathing

  • To open the airway, lift the chin forward with the fingers of the one hand and tilt the head backwards with other hand on the forehead.

Note:
Do not do this where a neck injury is suspected – refer below for management of suspected neck injury.


  • Ensure airway is open throughout resuscitation.
  • If there is no normal breathing, attempt 2 respirations with bag-valve-mask resuscitator and face mask.
  • The administered breaths must cause visible chest rising in patient. If not, reposition and try again once and proceed to next step.
  • Repeat the cycle of 30 compressions followed by 2 respirations for 5 cycles and then re-assess for a pulse.
  • If advanced airway is placed, administer 1 breath every 6 seconds without interrupting chest compressions. Avoid excessive ventilation.
  • Oxygenate with 100% oxygen.
  • Where neck injury is suspected:
    • Do not perform a chin lift or head tilt manoeuvre if a neck injury is suspected
    • To open the airway, place your fingers behind the jaw on each side.
    • Lift the jaw upwards while opening the mouth with your thumbs (jaw thrust).
    • Maintain in line cervical spine immobilisation.

Initiate fluids, IV/IO access

LoE: IIbiii

  • Sodium chloride 0.9%, IV
    • Administer a bolus of 1 litre during CPR if an increase in preload may benefit the patient, e.g., hypovolaemic shock, distributive shock, haemorrhagic shock.
    • Administer fluid cautiously during CPR if an increase in the preload could be detrimental, e.g., massive pulmonary embolism or cardiac tamponade.

LoE: IIIbiv

If pulseless with shockable rhythm (ventricular fibrillation/tachycardia)

  • Defibrillate, as indicated per algorithm.
  • Immediately resume CPR, starting with chest compression.
  • Continue CPR for 2 minutes.
  • Administer adrenaline (epinephrine) as per algorithm and directions below (Immediate emergency medicine treatment).
  • Seek reversible cause of arrest.
  • Continue CPR until spontaneous breathing and/or pulse returns.
  • For management of ventricular fibrillation or pulseless ventricular tachycardia that is unresponsive to defibrillation:
  • Amiodarone, IV bolus, 300 mg, 2 minutes after adrenaline (epinephrine) dose.
    • Follow by a bolus of 10 mL sterile water or sodium chloride 0.9%.
    • Patient remains in a shockable rhythm following further 2 minutes of CPR, a defibrillation shock, another adrenaline (epinephrine) dose, and another 2 minutes of CPR (5 cycles of 30:2): Amiodarone, IV bolus, 150 mg.

LoE: IIbv

If pulseless with non-shockable rhythm

  • Immediately resume CPR. Starting with chest compression.
  • Continue CPR for 2 minutes.
  • Administer adrenaline as per algorithm.
  • Seek reversible cause of arrest.
  • Continue CPR until spontaneous breathing and/or pulse returns.

Immediate emergency medicine treatment

Adrenaline (epinephrine) is the mainstay of treatment and should be given immediately, IV or intra-osseous, when there is no response to initial resuscitation or defibrillation.

  • Adrenaline (epinephrine), 1:1 000, 1 mL, IV immediately, as a single dose.
    • Flush with 5–10 mL IV of sterile water or sodium chloride 0.9%.
    • Repeat every 3–5 minutes during resuscitation.

If no IV line is available:

  • Adrenaline (epinephrine), intra-osseous (IO), 1:1000, 1 mL, via IO line.
    • Flush with 5–10 mL of sterile water or sodium chloride 0.9%.
    • Repeat every 3–5 minutes during resuscitation.

LoE: IVbvi

ADDITIONAL GUIDANCE

Continue CPR until spontaneous breathing and/or heart beat returns. Assess continuously (every 2 minutes) until the patient shows signs of recovery.

Termination of resuscitation:

  • The decision to stop CPR attempts depends on the specifics of the individual patient and should be based on clinical judgement.
  • Consider stopping resuscitation attempts and pronouncing death if there is incurable underlying disease, or if asystole > 20 minutes (in the absence of the factors below).

LoE: IIIbvii

Consider carrying on for longer especially with:

  • hypothermia and drowning
  • poisoning or medicine overdose
  • neurotoxic envenomation (e.g. black and green mamba or Cape cobra snakebite) – see: Snakebites

This decision should take into consideration the potential risk that CPR poses to the rescuer e.g. infectious diseases.

Click here for the pdf.

Click here for the Supporting NEMLC report and reviews_(2020-4 review cycle).


Standard Treatment Guidelines And Essential Medicines List For South Africa, Adult Hospital level, 2020-4_Version 1_June 2024

Chapter 20: Emergencies and Injuries

Drugs mentioned

ICD-10 codes

NeoHealth® ID 19116 · updated 3/13/2025