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Diarrhoea, Acute in Children

Description General Measures Medicine Treatment Referral CAUTION There is no place for anti-diarrhoeal preparations in the treatment of acute diarrhoea in children or in dysentery. ICD-10 code: A09.0/A09.9 DESCRIPTION A sudden onset of increased frequency of stools that are looser than normal, with or without vomiting. Commonly caused by a virus but may be caused by bacteria or parasites. The cau

Description

General Measures

Medicine Treatment

Referral


CAUTION
There is no place for anti-diarrhoeal preparations in the treatment of acute diarrhoea in children or in dysentery.


ICD-10 code: A09.0/A09.9

DESCRIPTION

A sudden onset of increased frequency of stools that are looser than normal, with or without vomiting. Commonly caused by a virus but may be caused by bacteria or parasites. The cause of acute diarrhoea cannot be diagnosed without laboratory investigation. It may be an epidemic if many patients are infected at the same time.

GENERAL MEASURES

  • Assess and manage dehydration according to the table below.
  • All children with severe dehydration require referral. Begin management for dehydration immediately whilst awaiting referral (see below).
  • All children should be assessed and treated for associated conditions e.g. hypothermia, convulsions, altered level of consciousness, respiratory distress, surgical abdomen.

Special types of diarrhoea

Click on the image to enlarge

Click on the image to enlarge.

Child should return immediately if:

  • condition does not improve
  • fever develops
  • condition deteriorates
  • eyes sunken
  • poor drinking or feeding
  • slow skin pinch
  • blood in stool

MEDICINE TREATMENT

The following children should receive ceftriaxone prior to referral:

  • Neonates with severe dehydration.
  • Children with Severe Acute Malnutrition (SAM) AND severe dehydration or shock.
  • Ceftriaxone, IM/IV, 100 mg/kg/dose immediately as a single dose. See dosing table.
    • For IM administration: do not inject more than 1 g at one injection site.

LoE:IVb8

  • For IV administration: Doses greater than 2 g must be given in two divided doses (i.e. 12 hourly), preferably by intravenous infusion over 30 minutes. 

LoE:IVb9 


CAUTION: USE OF CEFTRIAXONE IN NEONATES AND CHILDREN
- If neonate is suspected to have a serious bacterial infection, give ceftriaxone, even if jaundiced.
- Avoid giving calcium-containing IV fluids (e.g. Ringers Lactate) together with ceftriaxone:
   - If ≤ 28 days old, avoid calcium-containing IV fluids for 48 hours after ceftriaxone administered.
   - If > 28 days old, ceftriaxone and calcium-containing IV fluids may be given sequentially provided the giving set is flushed thoroughly with sodium chloride, 0.9% before and after.
   - Preferably administer IV fluids without calcium contents.
- Always include the dose and route of administration of ceftriaxone in the referral letter.


In children who are able to take oral medication:

  • Zinc (elemental), oral 10 mg/day for 14 days

AND

  • Homemade sugar and salt solution (SSS) for use at home to prevent dehydration.

LoE:IVb10 


Homemade sugar and salt solution (SSS)
½ level medicine measure of table salt
plus
8 level medicine measures of sugar
dissolved in 1 litre of boiled (if possible) then cooled water
(1 level medicine measure = approximately 1 level 5 mL teaspoon)


REFERRAL

  • Severe dehydration: Failure to maintain hydration with oral fluids/feeds, i.e. continued dehydration despite managing with “Plan B: Some dehydration”.
  • Children with general danger signs, e.g.:
    • convulsions
    • altered level of consciousness
    • intractable vomiting
    • inability to feed or drink
  • Children with dysentery if:
    • < 12 months of age
    • signs of dehydration
  • Malnourished children.
  • Suspected acute abdomen or other surgical problem.

Click here to access the pdf.

Click here for the  NEMLC Recommendations for medicine amendments (2020-4 review cycle).


Standard Treatment Guidelines And Essential Medicines List For South Africa, Primary Healthcare, 2020-4_Version 1_June 2024

Chapter 2: Gastro-Intestinal Conditions, 2.9 Diarrhoea, 2.9.1 Diarrhoea, Acute in Children

Drugs mentioned

ICD-10 codes

NeoHealth® ID 20008 · updated 2/10/2025