Potassium Citrate

Registered South African indications: 

• Inflammatory conditions of the bladder
• Prophylaxis of crystalluria

Contraindications

• Hypersensitivity to the active ingredient or any of the excipients
• Renal impairment
• Hyperkalaemia
• Ventricular arrhythmia
• Addison's disease

Cautions

• Pregnancy
• Breastfeeding
• Elderly
• Cardiac dysfunction
• Diabetes mellitus
• Fructose intolerance
• Glucose-galactose malabsorption
• Sucrase-isomaltase insufficiency

Forms avail. in SA and covered in this monograph: liq

Urinary alkaliniser
-To alleviate inflammatory condition of the bladder
Prophylaxis of crystalluria

• Oral (liq): 0.83g (10ml), 8hrly

To be diluted with water and taken with or immediately after meals

Paed. forms avail. in SA and covered in this monograph: liq

Urinary alkaliniser
-To alleviate inflammatory condition of the bladder
Prophylaxis of crystalluria

Younger than 12 years

• Not established for use

Between 6-12 years

• Oral (liq): 0.42g (5ml), 8hrly

Older than 12 years

• See adult dosage

To be diluted with water and taken with or immediately after meals

Pregnancy

• Caution
• No adverse effects are anticipated at recommended doses when used for initial symptomatic relief only

Breastfeeding

• Caution
• Potassium is excreted into breast milk. No adverse effects are anticipated at recommended doses when used for initial symptomatic relief only

Renal Impairment

• Contraindicated

Hepatic Impairment

• No dose adjustment recommended

Elderly

• Caution; no dose adjustment recommended

Porphyria Information

• Not porphyrinogenic (NP)

Drugs in Sport

• Permitted - No warnings

Gastrointestinal Disorders

• Nausea and vomiting
• Gastric irritation
• Diarrhoea
• Abdominal cramps

Endocrine and Metabolic Disorders

• Metabolic alkalosis

Musculoskeletal Disorders

• Muscle typertonicity
• Twitch
• Tetany

• Cardiac glycosides
• Agents that increase serum potassium
• Potassium sparing agents
• Sympathomimetics
• Nitrofurantoin
• Methamamine
• Salicylates
• Tetracyclines 
• Barbiturates

None routine. Specific cases may require

• Electrolytes
• Full blood count
• Renal function
• Urinary pH

Potassium citrate renders the urine less acidic, after metabolism.

Potassium citrate is available in several formulations. Please note the list below gives examples of products which are available and is not necessarily comprehensive. The listing of a product does not constitute endorsement of the product by EMGuidance; likewise, failure to list a product does not imply that EMGuidance disapproves of the product. This information is put together on the basis of the National Government's Medicines Price Registry at the time of publication

Liquid (per 15ml) 1.250g

• Barrs Potassium Citrate Mixture BP (Barrs)
• Propan Mist Pot Cit Simplex (Adcock)