Articles
662 entriesClinical reviews and commentary
- Strategies for positive leadership attitude among operational managers post-COVID-19 at primary health care clinics in the City of JohannesburgThe quality of the leadership shown by operational managers was tested during coronavirus disease 2019 (COVID-19).→
- Streamlining healthcare operations with multicloud-by-designIs Cloud Tech Holding Hospitals Back? Dell Expert Warns of Hidden Risks in Healthcare's Multicloud Boom!→
- Strengthening digital health capacities through blended learningIn many low- and middle-income countries, national digital health teams face a familiar reality: fragmented systems, overlapping applications and growing pressure to support health workers with reliable, actionable data.→
- Study finds why 'night owls' have a higher risk for depression than 'early risers'.Night owls may face higher depression risk due to poor sleep, less mindfulness, and more alcohol use, new study finds.→
- Study links alcohol consumption to more severe nut allergy reactionSevere Allergy Warning: Study Links Tree Nuts & Food to Most Anaphylaxis Cases—Could This Speed Up Emergency Diagnosis?→
- Study shows liraglutide results in increased insulin sensitivity independent of weight lossA new study demonstrates that a glucagon-like peptide-1 receptor (GLP-1R) agonist, a member of a class of medication used to treat Type 2 diabetes and obesity, can lead to a rapid improvement in insulin sensitivity.→
- Study shows nearly 300% increase in ADHD medication errorsAttention-deficit/hyperactivity disorder (ADHD) is among the most common pediatric neurodevelopmental disorders. In 2019, nearly 10% of United States (U.S.) children had a diagnosis of ADHD.→
- Subclinical Primary Aldosteronism and Cardiovascular Health: A Population-Based Cohort StudyPrimary aldosteronism, characterized by overt renin-independent aldosterone production, is a common but underrecognized form of hypertension and cardiovascular disease. Growing evidence suggests that milder and subclinical forms of primary aldosteronism are highly prevalent, yet their contribution to cardiovascular disease is not well characterized.→
- Substitution of nurses for physicians in the hospital setting for patient, process of care, and economic outcomesThe demand for health services to deliver hospital‐based care has increased due to an ageing population, more complex healthcare needs, comorbidities, and increasing healthcare costs.→
- Subtle signs of multiple sclerosis may appear years before onsetA recent study in Canada found that people who developed multiple sclerosis (MS) had significantly higher use of healthcare services up to 15 years before symptom onset, with a 76% increase in mental health visits and a 159% increase in psychiatric visits. This suggests MS develops earlier than previously thought. The findings could lead to earlier diagnosis and management of the condition.→
- Surgical approaches for inserting hemiarthroplasty of the hip in people with hip fracturesA review of 27 studies on hip hemiarthroplasty surgical approaches (anterior, lateral, posterior) for hip fractures found no clear evidence of superiority for activities of daily living, quality of life, mobility, mortality, or pain within four months. Most evidence was very uncertain, highlighting the urgent need for larger, high-quality trials.→
- Systematic review and meta-analysis of the non-specific and broader impact of respiratory vaccines on acute lower respiratory infections in young childrenGrowing evidence suggests that vaccines targeting respiratory pathogens have non-specific and broader effects.→
- Systemic lupus erythematosus and risk factors for adverse outcomes in pregnancySystemic lupus erythematosus (SLE) directly impacts pregnancy outcomes.→
- Systemic pharmacological treatments for chronic plaque psoriasis: a network meta‐analysisPsoriasis is an immune‐mediated disease with either skin or joint manifestations, or both, and it has a major impact on quality of life.→
- Takayasu’s arteritis associated with tuberculosis: a retrospective studyTakayasu Arteritis and Tuberculosis: Study Unveils Key Differences in Symptoms and Aortic Damage!→
- Tantrums in young children could be linked to ADHD, study findsEarly Emotional Struggles Linked to ADHD & Behaviour Issues by Age 7—Study Reveals Key Warning Signs!→
- Teenage Years Crucial for Depression InterventionNew hope for teens: Depression more flexible in youth, making early treatment more effective.→
- Telehealth offers advantages for treating children with feeding disordersMany neurotypical and most neurodivergent children struggle with feeding difficulties. This does not just affect the child – it impacts the whole family.→
- Telephone-based care can prevent loneliness and depression finds major studyStructured telephone-based psychological care can prevent loneliness and depression, according to an NIHR-funded study.→
- Telepsychiatry practice uses AI to reduce time to complete session notes by 23%AI Revolutionizing Therapy: How Ambient Listening Tech is Enhancing Clinical Notes & Patient Focus!→
- Telomerase RNA component knockout exacerbates Staphylococcus aureus pneumonia by extensive inflammation and dysfunction of T cellsTelomerase RNA Deficiency Linked to Severe Pneumonia: Study Reveals Key Role of Terc in Immunity and Aging!→
- Tests for diagnosis of postpartum haemorrhage at vaginal birthCan We Better Detect Postpartum Haemorrhage? Study Evaluates Accuracy of Diagnostic Methods to Prevent Maternal Deaths!→
- Thank You for an Incredible 2024!As we close out 2024, we at EMGuidance would like to express our deepest gratitude to our valued healthcare professionals and partners.→
- The Aldehyde Dehydrogenase 2 rs671 Variant Enhances Platelet Activation and Arterial ThrombosisAcute myocardial infarction (AMI) caused by thrombosis is a major cause of mortality.→
- The Competency of Nurses in Basic Life Support at District Hospitals in Cape Town, South AfricaImproving Cardiac Arrest Survival: Focus on Nurses' BLS in District Hospitals.→
- The Evolution of Obesity Pharmacotherapy from Sympathomimetics to Incretin-based TherapiesThis review explores the transition from traditional agents like phentermine to incretin-based therapies such as semaglutide and tirzepatide. It highlights the shift from short-term appetite suppression to sustained pharmacological management of obesity and its comorbidities.→
- The National Department of Health Circular Regarding the Availability of FlucytosineThe National Department of Health has announced that flucytosine (NSN 222001495) is now available again through PPQ.→
- The National Health Insurance Act: Possible private health funding reform scenariosSouth Africa's National Health Insurance (NHI) Act will profoundly impact healthcare. This article explores its effect on the private health funding sector, examining two scenarios: a "passive" decline risking unsustainability, versus an "active" approach with reforms to maintain viability during the NHI transition.→
- The Roles and Mechanisms of Gut Microbiota in Food AllergyRecent research reveals that the increasing prevalence of food allergies (FA) is due in part to changes in the commensal microbiome. Studies in humans have shown that compared with healthy controls, individuals have distinct gut microbiomes during the onset and progression of FA.→
- The adequacy and safety of anticoagulation therapy with warfarin at the medical outpatient clinic of an academic hospitalWarfarin Monitoring Challenges: INR Testing Barriers Put Patients in Resource-Limited Settings at Risk!→
- The association between comorbid conditions and CD4+ T-cell counts with in-hospital mortality of patients with moderate to critical COVID-19 diseaseBackground. COVID‑19 presents with variable severity, and identifying accessible prognostic markers is critical in resource-limited settings such as South Africa (SA).→
- The association between serum magnesium levels and hypertensive disorders of pregnancyEvidence on circulating magnesium and hypertensive disorders of pregnancy in African populations is limited.→
- The association of bearing surface materials with the risk of revision following primary total hip replacement: A cohort analysisDo Implant Materials Affect Hip Replacement Success? Study Analyzes Revision Rates by Bearing Surface Types!→
- The associations of candidate gene polymorphisms with aspirin resistance in patients with ischemic disease: a meta-analysisAspirin Resistance Mystery: Can Gene Polymorphisms Unlock the Key to Personalized Treatment for Ischemic Diseases?→
- The current and future value of EMR solutionsTo succeed, EMR systems must go beyond initial deployment to an ongoing journey of optimisation.→
- The dawn of preventing respiratory syncytial virus lower respiratory tract infections in childrenRSV Prevention Breakthrough: New Antibody & Maternal Vaccine Could Reduce Infant Hospitalizations in South Africa!→
- The future of pharmacy in South Africa: embracing the digital revolutionSA’s health system faces big shifts—NHI, 5IR, and AI demand a stronger role for pharmacy in quality care.→
- The impact of simulated clinical immersion on nursing students’ preparedness for end-of-life care in older adultsWith the global population ageing, there is an urgent need for nurses competent in providing end-of-life (EOL) care for older adults.→
- The implementation of community-oriented primary care in the Cape Metro Health DistrictA study explored the implementation of a community-oriented primary care (COPC) framework piloted at four learning sites in Cape Metro, Western Cape.→
- The lifeworld of families of mental health care users in rural South Africa: A phenomenological studyFamilies on the Frontline: Rural South Africa's Mental Health Crisis Puts Untrained Caregivers to the Test!→
- The pill and the profession: the evolving role of pharmacists in oral contraceptive access for women in SAOral contraceptives (OCs) play a key role in reproductive health and family planning, yet their use and accessibility in South Africa remain shaped by sectoral dynamics, socioeconomic factors, and persistent systemic barriers.→
- The plight of unemployed pharmacists and pharmacist’s assistants.Pharmacist Job Market Shrinking: PSSA Calls for National Action to Tackle Employment Crisis & Secure Fair Wages!→
- The role of pharmacomicrobiomics in HIV prevention, treatment, and women’s healthCould the Microbiome Hold the Key to Better HIV Treatment? New Insights into Its Impact on ART & PrEP Efficacy!→
- The role of vitamin C on the skinVitamin C, obtained solely through diet, is crucial for skin health, promoting cell differentiation and reducing melanin. Its antioxidant properties protect against sun damage, ageing, pigmentation issues, and may play a role in some skin cancers. Research suggests topical application offers greater clinical benefit than oral intake for various skin conditions, highlighting its versatile importance in dermatology.→
- The role of vitamin D in glycaemic control: a review of randomised controlled trialsVitamin D deficiency and diabetes mellitus are both global health concerns with increasing prevalence.→
- The use of a urine lipoarabinomannan test in clinical decision-making regarding empiric tuberculosis treatmentTB in HIV is deadly. Urine LAM helps diagnose, but negatives can mislead when symptoms still suggest TB.→
- The use of lenvatinib and pembrolizumab after platinumbased chemotherapy in advanced endometrial cancerBreakthrough in Endometrial Cancer? Lenvatinib & Pembrolizumab Show Promise in Advanced Cases!→
- Therapeutic Drug MonitoringTherapeutic Drug Monitoring: Precision Medicine for Safer, More Effective Treatments!→
- Third meeting of the International Health Regulations (2005) Emergency Committee regarding the upsurge of mpox 2024WHO Declares Mpox Still a Global Health Emergency—New Recommendations Issued After Latest IHR Committee Meeting!→
- This high-sugar fruit may actually lower diabetes riskMangos beat low-sugar snacks in a study, improving blood sugar and body fat in prediabetics.→