Articles
41 entriesClinical reviews and commentary
- Day 2 of Pregnancy Awareness Week – Empowering the Frontline of CarePregnancy Care Made Easier: Access Trusted, Expert-Verified Guidelines Instantly on EMGuidance!→
- Day 3 of Pregnancy Awareness Week – Medical Calculators for Precision CareBoost Pregnancy Care Decisions with EMGuidance! Access Time-Saving Calculators for C-Sections, Inductions & More!→
- Day 4 of Pregnancy Awareness Week – Prescribing Guidance for Safe CareSafe Prescribing for Pregnancy Made Easy! Access Expert Guidance & Key Resources on EMGuidance Today!→
- Day 5 of Pregnancy Awareness Week – Continuing Professional Development on EMGuidanceBoost Your Pregnancy Care Expertise! Earn CPD Points with Accredited Courses on EMGuidance—Stay Ahead in Best Practices!→
- Deep learning diagnosis plus kinematic severity assessments of neurodivergent disordersEarly diagnosis of neurodivergent disorders (NDD) remains challenging. New research suggests analysing subtle movement patterns at millisecond scales holds crucial cognitive information. Using deep learning on raw kinematic data, researchers could highly accurately identify individuals with ASD, ADHD, or comorbid conditions. Additionally, new biometrics (Fano Factor, Shannon Entropy) quantifying physiological fluctuations offer quantitative subtyping by severity, providing complementary tools for early evaluation and diagnosis.→
- Delayed initiation or reduced initial dose of calcineurin‐inhibitors for kidney transplant recipients at high risk of delayed graft functionKidney transplant is preferred for kidney failure, but delayed graft function (DGF) is more common in high-risk DCD donors. Optimal immunosuppressive strategies for DGF risk remain debated.→
- Denmark becomes First Country in the European Union to Eliminate Mother-to-Child Transmission of HIV and SyphilisDenmark has become the first European Union country to be certified by the WHO for eliminating mother-to-child transmission of HIV and syphilis.→
- Depression unveiled: a comprehensive review of pathophysiology and treatment advancesClinically, depression manifests through symptoms such as feelings of worthlessness, cognitive and sleep disturbances, and suicidal ideation, with major depression representing the predominant subtype.→
- Desmopressin for nocturnal enuresis in childrenA review of 95 studies on bedwetting found that desmopressin may reduce the frequency of wet nights compared to a placebo. Its effectiveness is similar to alarm therapy, although alarm therapy shows more sustained long-term success. Combining desmopressin with alarm therapy or anticholinergics may be slightly more effective than desmopressin alone. The overall evidence quality remains low or very low.→
- Detect early TB infection, evaluate contacts for TB (DETEC-TB)Tuberculosis (TB) is a leading cause of death from infectious disease, with 1.25 million deaths in 2023. Among the estimated 10.8 million people who developed TB in 2023, only 75% were diagnosed and reported to national programs.→
- Diabetes knowledge levels among patients in Mhlontlo, South AfricaThere is a high prevalence of diabetes in South Africa and a related increase in poor treatment outcomes among people with diabetes. Poor glycaemic control is often associated with a lack of knowledge of self-management.→
- Digital Mental Health Tools Need Human TouchNew research: Human presence, even scripted, significantly boosts engagement and empathy in online mental health interviews.→
- Digital pathology cleared for use in cancer screening programmesThe UK Government has approved the use of digital pathology to help speed up analysis of cancer screening samples.→
- Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health careDigital tracking via mobile devices, paired with clinical decision support and targeted communication, may boost service delivery and outcomes.→
- Diphtheria Cases Rise in South Africa: What You Need to KnowUrgent Diphtheria Alert: 40 Cases Detected in South Africa—Clinicians Advised to Stay Vigilant & Test Suspected Cases!→
- Diphtheria Situational Report (Week 8 Of 2025)Respiratory Diphtheria Alert: 29 Cases & 33 Carriers Detected in South Africa—Western Cape Most Affected!→
- Diphtheria in South Africa: What You Need to KnowDiphtheria is a contagious, potentially life-threatening bacterial infection caused by toxin-producing strains of *Corynebacterium* and occurs in two forms: respiratory and cutaneous.→
- Diphtheria in South Africa: What You Need to KnowDiphtheria Alert: Understanding the Risks, Symptoms, and Forms of This Potentially Life-Threatening Infection!→
- Diphtheria situational report (week 11 of 2026)Respiratory diphtheria is a vaccine-preventable illness caused by toxigenic C. diphtheriae (and more rarely C. ulcerans or C. pseudotuberculosis), and can occur in persons of all ages.→
- Diphtheria situational report (week 12 of 2026)Respiratory diphtheria is a vaccine-preventable illness caused by toxigenic C. diphtheriae (and more rarely C. ulcerans or C. pseudotuberculosis), and can occur in persons of all ages.→
- Diphtheria situational report (week 14 of 2026)Respiratory diphtheria is a vaccine-preventable illness caused by toxigenic C. diphtheriae (and more rarely C. ulcerans or C. pseudotuberculosis), and can occur in persons of all ages.→
- Diphtheria situational report (week 15 of 2026)Between 29 December 2025 and 12 April 2026, 18 confirmed cases of respiratory diphtheria and three asymptomatic carriers of toxigenic C. diphtheriae have been identified in South Africa. All respiratory cases and carriers were from the Western Cape. Click here to access the article.→
- Diphtheria situational report (week 18 of 2026)Respiratory diphtheria is a vaccine-preventable illness caused by toxigenic C. diphtheriae (and more rarely C. ulcerans or C. pseudotuberculosis), and can occur in persons of all ages.→
- Diphtheria situational report (week 2 of 2026)Since the last situational report (week 1, 2026), the following updates are included in this report.→
- Diphtheria situational report (week 3 of 2026)Respiratory diphtheria is a vaccine-preventable illness caused by toxigenic C. diphtheriae (and more rarely C. ulcerans or C. pseudotuberculosis), and can occur in persons of all ages.→
- Diphtheria situational report (week 46 of 2025)Respiratory diphtheria is a vaccine-preventable illness caused by toxigenic C. diphtheriae (and more rarely C. ulcerans or C. pseudotuberculosis), and can occur in persons of all ages.→
- Diphtheria situational report (week 46 of 2025)Respiratory diphtheria is a vaccine-preventable illness caused by toxigenic C. diphtheriae (and more rarely C. ulcerans or C. pseudotuberculosis), and can occur in persons of all ages.→
- Diphtheria situational report (week 47 of 2025)The majority of confirmed cases and carriers (74%, 101/137) were from the Western Cape, comprising 57 respiratory diphtheria cases and 44 asymptomatic carriers.→
- Diphtheria situational report (week 48 of 2025)Respiratory diphtheria is a vaccine-preventable illness caused by toxigenic C. diphtheriae (and, more rarely, C. ulcerans or C. pseudotuberculosis) and can occur in persons of all ages.→
- Diphtheria situational report (week 52 of 2025)Respiratory diphtheria is a vaccine-preventable illness caused by toxigenic C. diphtheriae (and more rarely C. ulcerans or C. pseudotuberculosis), and can occur in persons of all ages.→
- Diphtheria situational report (week 7 of 2026)The majority of confirmed cases and carriers (77%, 119/155) were from the Western Cape, comprising 69 respiratory diphtheria cases and 50 asymptomatic carriers.→
- Diphtheria situational report (week 8 of 2026)Respiratory diphtheria is a vaccine-preventable illness caused by toxigenic C. diphtheriae (and more rarely C. ulcerans or C. pseudotuberculosis), and can occur in persons of all ages.→
- Direct stroke unit access versus a hub-and-spoke model with telemedicine-assisted CTTimely access to reperfusion therapy is critical in acute ischaemic stroke, with intravenous thrombolysis within the first 60 min (“golden hour”) yielding the greatest clinical benefit.→
- Dispelling the Myths: Electronic Prescribing in South Africa - Clarity, Compliance, and Patient SafetyUnderstand South Africa's legal requirements for electronic prescriptions and how EMGuidance Script ensures compliance and patient safety.→
- Doctors just found a way to slow one of the deadliest prostate cancersA targeted drug combo slashes prostate cancer progression and ushers in a new era of personalised treatment.→
- Doxycycline Now More Accessible for Malaria ChemopreventionMalaria prevention made easier—doxycycline reclassified as Schedule 2 in SA, no prescription needed.→
- Drivers of COVID-19 infections: Perspectives of managers in the Gauteng Department of Health, South AfricaThis study investigated the perceptions and experiences of Gauteng Department of Health (GDoH) senior managers about factors that contributed to the high incidence of coronavirus disease 2019 (COVID-19) in Gauteng.→
- Drug for diabetes and kidney disease may also lower heart attack, stroke risksGame-Changing Discovery: Common Diabetes & Kidney Disease Drug Also Cuts Stroke & Heart Attack Risk!→
- Drug treatment for myotoniaUpdated review explores treatments for myotonia—a disabling muscle stiffness in genetic disorders—highlighting key therapies.→
- Dual combination therapy versus long‐acting bronchodilators alone for chronic obstructive pulmonary diseaseCOPD is a global lung disease marked by airflow obstruction and driven by diverse factors like smoking, TB history, and pollution.→
- Duo biologic therapy using mepolizumab and omalizumab in refractory ABPAAllergic bronchopulmonary aspergillosis (ABPA) presents with a wide range of symptom severity.→