Articles
42 entriesClinical reviews and commentary
- ICD-11 2026 ReleaseInternational Classification of Diseases 11th Revision.→
- INnovative Steroid Treatment to reduce Asthma development in children after first-time Rhinovirus-induced wheezing (INSTAR)A study is investigating if a short course of oral dexamethasone can prevent recurrent wheezing and asthma in steroid-naïve infants (3-23 months) experiencing their first rhinovirus-induced wheezing episode.→
- Immune checkpoint inhibitors and chemotherapy versus chemotherapy for early triple‐negative breast cancerBreast cancer is the most common type of cancer and the leading cause of cancer deaths in women worldwide (Sung 2021). In 2020, there were approximately 2.3 million new cases of breast cancer and 683,100 deaths→
- Impact of Y Chromosome Loss on the Risk of Parkinson's Disease and ProgressionThis study investigates the unclear role of Loss of Y chromosome (LOY) in Parkinson's disease (PD) onset and progression by examining blood LOY levels.→
- Impact of abdominal adipose tissue segmentation on radiomics-based prognostic evaluation using CT enterography in Crohn’s diseaseCrohn’s disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract, with increasing prevalence worldwide.→
- Impact of active case finding for tuberculosis with mass chest X-ray screening in Glasgow, Scotland, 1950–1963: An epidemiological analysisLessons from the Past: How a 1957 TB Screening Campaign in Glasgow Could Shape Modern High-Burden Strategies!→
- Impact of metabolic dysfunction on treatment responses to nucleos(t)ide analogues in chronic hepatitis BA study of over 4,500 chronic hepatitis B patients found that having metabolic diseases (like diabetes or obesity) is associated with a lower biochemical and complete treatment response to nucleos(t)ide analogue drugs. The negative impact on treatment success was more pronounced with an increased number of metabolic diseases. This suggests that metabolic health is a critical factor in managing chronic hepatitis B.→
- Impacts of Reducing Sitting Time or Increasing Sit-to-Stand Transitions on Blood Pressure and Glucose Regulation in Postmenopausal WomenPublic health and clinical guidelines identify the importance of sedentary behaviours for cardiovascular diseases, particularly among postmenopausal women.→
- Implementation science derived from low- and middle-income countries is essential for advancing global healthGlobal health is at a crossroads. As global health programs are scaled back and funding grows uncertain.→
- Implementing Active Surveillance for Tuberculosis: A Quality Improvement ProjectThis study evaluates how CHWs can implement active TB surveillance in South Africa, a country burdened by severe TB and MDR-TB epidemics.→
- Improving Transparency in Clinical Trial ReportingCONSORT & SPIRIT 2025 launch—new guidelines aim to boost trial transparency, quality & impact.→
- In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
- In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
- In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
- In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
- In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
- In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
- In defence of South Africa’s National Health Research Ethics Council guidelines on heritable human genome editingHeart Failure Breakthrough? FINEARTS-HF Study Explores How Finerenone Impacts Different Ejection Fractions!→
- In-ear microphones could help doctors 'listen' for early signs of Alzheimer'sCan Earbuds Detect Alzheimer’s Early? Scientists Explore Hearables for Diagnosing Neurodegenerative Diseases!→
- Incidence of local anesthetic systemic toxicity in patients receiving bupivacaine infiltration analgesia for total joint arthroplasty under general anesthesiaHidden Risk in Surgery: Can Local Infiltration Analgesia Lead to Fatal Toxicity? New Research Explores the Danger!→
- Incidence rates of hepatocellular carcinoma based on risk stratification in steatotic liver disease for precision medicine: A real-world longitudinal studySteatotic Liver Disease and Cancer: Study Targets Critical Gaps in Subgroup Incidence Rates to Guide Public Health Action!→
- Incorporating Behavioral Science in Medication Adherence CommunicationSilent threat: Hypertension often goes untreated due to poor adherence—new strategies urgently needed.→
- Increases in vaccine-preventable disease outbreaks threaten years of progress, warn WHO, UNICEF, GaviWHO & UNICEF sound alarm—vaccine-preventable diseases rise as immunization efforts face major setbacks.→
- Infant Botulism Outbreak Linked to Infant FormulaInfant botulism happens when a baby swallows Clostridium botulinum spores that grow in the gut and make toxin.→
- Infant formula poisonings: 36 cases reported in UK as experts issue advice to doctorsAt least 36 cases of babies becoming sickened from tainted infant formula supplies have been reported in the UK, officials say.→
- Inflammatory diets, ultra-processed foods may increase Crohn's disease riskInflammatory bowel disease (IBD) is a group of chronic conditions that damage the intestines and can cause uncomfortable symptoms.→
- Influences of Western Cape community service doctors’ choice regarding public, rural practiceDespite South Africa's compulsory community service aimed at boosting rural healthcare, few doctors intend to stay in these areas (8%). A Western Cape study found rural upbringing (6.5x more likely) and rural placements (7.7x/3.5x more likely) significantly influenced retention. Policies should prioritise rural background students and placements, alongside ensuring personal safety, job satisfaction, and mental health in rural facilities.→
- Intermittent fasting may not aid weight loss, large review findsAdditional research into this area may be helpful to understand the full effects of intermittent fasting and how it may help people with certain conditions.→
- Interruption in the Supply of Betamethasone Disodium Phosphate 4mg/ml InjectionWould you like a shorter version for email headers or an even more formal version for departmental memos?→
- Intervention to Enhance Resilience Among Nurse Managers: A Systematic ReviewNurse managers are vital, high-stress healthcare links; COVID-19 amplified this, proving their resilience is critical for their well-being and team.→
- Interventions for central serous chorioretinopathy: a network meta‐analysisA review of 67 RCTs on Central Serous Chorioretinopathy (CSC) found no single treatment definitively superior. While low-dose photodynamic therapy, supplements, and eplerenone showed potential for improving vision, the evidence is limited by small, poorly reported trials and low confidence in findings, highlighting a need for larger, high-quality research.→
- Interventions for fertility preservation in women with cancer undergoing chemotherapyFor cancer patients undergoing chemotherapy, a review found that GnRH agonists may significantly reduce ovarian insufficiency in breast cancer, though other evidence is very uncertain. There's no clear evidence on live births or overall survival for either ovarian suppression or ovarian hyperstimulation with oocyte/embryo freezing, nor direct comparisons between the two.→
- Intraoperative hypotension and postoperative risks in non-cardiac surgeryManaging Intraoperative Hypotension: Meta-Analysis Examines Best Strategies to Reduce Post-Surgery Complications!→
- Investigating the role of knowledge management in the pharmaceutical sectorPoor knowledge management in pharma risks patient safety—linked to delays, errors, and poor outcomes.→
- Iron deficiency anaemia: Managing symptoms and supporting self-careFighting Iron Deficiency: New Guide Equips Pharmacists to Lead the Charge in Managing Anaemia Worldwide!→
- Is autism on the rise? Expert fact-checks recent claimsSocial media has boosted autism awareness, coinciding with an apparent rise in US diagnoses. This increase, however, isn't an "epidemic." Experts confirm it's due to broader diagnostic criteria, improved screening, and increased awareness, not primarily environmental factors, despite some claims.→
- Is brain inflammation at the core of cognitive decline? What latest research saysNew research links brain inflammation and herpes viruses to dementia risk, while vaccines and anti-inflammatories may help prevent it.→
- Is coffee good for your heart health? 3 studies offer insightsIs Your Coffee Helping or Harming Your Heart? Latest Research Unveils Caffeine’s Surprising Effects on Cardiovascular Health!→
- Is excessive sleepiness as we age a warning sign of dementiaNew study links excessive sleepiness in women over 80 to double the risk of developing dementia within 5 years.→
- Is your Patient’s Asthma Well-controlled?This review highlights the critical "perception gap" in asthma management, where many patients believe their condition is controlled despite failing to meet objective clinical criteria, and explores strategies like validated assessment tools and patient empowerment to achieve true control.→
- Ischaemic Heart Disease: Pathophysiology, Diagnosis, and Therapeutic StrategiesIschaemic heart disease (IHD) remains the leading cause of global mortality, yet it is largely preventable through the targeted management of modifiable risk factors. This update explores contemporary diagnostic tools, therapeutic strategies, and the critical role pharmacists play in optimising patient outcomes.→
- It’s time to talk to emergency medical dispatchersPerformance feedback and patient outcome follow-up are essential in emergency medical services.→