Articles
662 entriesClinical reviews and commentary
- NICD Study Calls For Heightened Awareness Against RabiesRabies alert! The PHBSA report warns: this dog-borne, almost always fatal virus demands immediate awareness→
- NICD’s GERMS-SA Surveillance Report Reveals A Rise In Vaccine-Preventable DiseasesSouth Africa’s Health Gains at Risk? NICD Report Reveals a Surge in Vaccine-Preventable & HIV-Related Diseases!→
- NOURISH-US: a mixed-methods, randomized crossover study of a program designed to reduce the financial burden of food allergyFood allergy imposes considerable financial costs on families, but few programs are available to offset these costs→
- Natalizumab for multiple sclerosisNatalizumab (NTZ) is the first monoclonal antibody approved for the treatment of highly active relapsing‐remitting multiple sclerosis (RRMS).→
- National Cancer Registry And Partners To Unveil Cancer Survivors Month PlansThe NCR, NICD, Living With Cancer South Africa, and CANSA will pre-launch Cancer Survivors Month on May 27, 2025, to celebrate survivors and support those fighting cancer.→
- Nearly 50 million people sign up call for clean air action for better healthOver 47 million unite globally, urging urgent action against air pollution—one of the deadliest threats to human health.→
- Neck Dissection for Advanced Laryngeal CancerLaryngeal cancer care under review, should elective neck dissection be done up front or after nodal relapse?→
- Nestlé recalls several SMA Infant Formula and Follow-On Formula because of the presence of cereulide (toxin)Nestlé is recalling the above products. Point of sale notices will be displayed in all retail stores that are selling these products.→
- Nestlé removes infant formula from SA and other countries over toxin riskSwiss giant Nestlé is recalling some batches of its infant nutrition products, including SMA, BEBA and NAN formulas, in 25 countries due to possible contamination with a toxin that can cause nausea and vomiting.→
- Network meta-analysis of HIF-prolyl hydroxylase inhibitors for anemia in dialysis-dependent and non-dialysis CKDHIF–prolyl hydroxylase inhibitors (HIF-PHIs) are oral alternatives to erythropoiesis-stimulating agents (ESAs) for anaemia in chronic kidney disease (CKD).→
- New Bioactive Compound for Difficult-To-Treat AllergiesNew research identifies a compound that effectively reduces symptoms and fatality risk in severe immune-triggered conditions like IBS, asthma, and migraines.→
- New CAR-T Therapy achieves positive results in a high proportion of patients with a refractory type of lymphomaBreakthrough! CAR30+ cell therapy hits 100% response, 50% remission in tough lymphoma cases.→
- New Content Partner: South African Nephrology SocietyWe’re excited to announce that the South African Nephrology Society Guidelines & Consensus Statements are now available in the Clinical Guideline Repository!→
- New Course Alert - Gastrostomy Feeding: Start-Up Basics and Navigating Between Different FeedsRefresh Your Knowledge on Gastrostomy Feeding→
- New Study Raises Concerns About the Safety of Long-term ADHD Medication Treatment in ChildrenA recent study reveals children and adolescents take ADHD medication for over three years on average, yet reliable safety data for these drugs only extends to one year of follow-up.→
- New WHO Guidance on Novel Snakebite Treatments PublishedThe World Health Organization has released the first set of Target Product Profiles (TPPs) to guide the development of next-generation snakebite treatments, including small molecule drugs and engineered antibodies.→
- New WHO and ITU standard aims to prevent hearing loss among gamersWHO & ITU Launch First Global Safe Listening Standard for Gamers to Prevent Hearing Loss Ahead of World Hearing Day 2025!→
- New WHO guidance calls for urgent transformation of mental health policiesWHO launches new guidance urging countries to reform mental health systems, as up to 90% receive no care in some regions.→
- New blood test shows promise in detecting 18 types of cancerA new blood test could be used for early detection of 18 different types of cancer, a new study published in the journal BMJ Oncology reports. In developing the test, the researchers focused on the proteome — the complete collection of proteins in the body.→
- New blood test shows promising potential for early cancer detectionBreakthrough Blood Test Detects 6 Cancers Early—Could TriOx Revolutionize Cancer Diagnosis?→
- New guide promotes safe, inclusive and child-friendly public spacesMillions of children living in towns and cities still lack access to public spaces.→
- New prevention tools and investment in services essential in the fight against AIDSNew guidelines recommending the use of lenacapavir as an additional pre-exposure prophylaxis (PrEP) option for HIV prevention.→
- New recall in Salmonella outbreak linked to dietary supplements containing moringa leaf powderA CDC food safety alert linked to moringa leaf powder.→
- New research highlights trends in ADHD diagnosesADHD Diagnoses Rising in Adults Since 2020 While Adolescent Rates Stabilize, New Study Reveals!→
- New resource to help countries count cases of suicide more accuratelyIn view of the challenges of providing accurate numbers of deaths by suicide, WHO has launched a new resource, Preventing suicide: a resource for strengthening suicide case registration.→
- New tool will hunt down tumours‘Metal detector’ for cancer? New PRRDetect tool spots vulnerable tumours—could revolutionise treatment!→
- New tool will hunt down tumoursNew PRRDetect ‘metal detector’ algorithm helps spot vulnerable tumours—paving the way for more personalised cancer treatment.→
- New trial to test device treating threatened miscarriageNIHR backs world-first device for threatened miscarriage with £1M funding—potential to save NHS £236M and help 150K women yearly.→
- Next-generation influenza vaccines could save millions of lives, finds WHOWhile current influenza vaccines help reduce the burden of disease, their effectiveness can vary by season, product, and population group. Protection is limited to one season.→
- Nipah Virus updatesNipah virus infection is caused by the zoonotic virus, Nipah virus (NiV), a member of the genus Henipavirus in the family Paramyxoviridae.→
- Nocturnal enuresis: A call for advocacyFrom Stigma to Science: Enuresis Uncovered—Why This Common Condition Is Still Underdiagnosed and Undertreated!→
- Nonsteroidal anti‐inflammatory drugs (NSAIDs) for acute renal colicNSAIDs remain a key option for managing renal colic pain in urolithiasis—updated Cochrane review highlights their effectiveness.→
- Notice 20 February 2025: Withdrawal of Phenobarbital 15mg/5ml 100ml Syrup from Contract (HP12-2023LQ/01.)Phenobarbital oral therapy is recommended in PHC and Paediatric STGs for seizures in infants, with syrup used when swallowing is an issue. Review the STGs and EML for full indications and prescribing guidance.→
- Novel MRI technique improves treatment for severe depressionUsing MRI and tracking to guide the delivery of magnetic stimulation to the brains of people with severe depression will see their symptoms ease for at least 6 months.→
- Novel Plasma Proteomic Markers and Risk of Venous ThromboembolismVenous thromboembolism (VTE), encompassing deep venous thrombosis (DVT) and pulmonary embolism (PE), is a common condition and the third most common life-threatening cardiovascular disease (CVD).→
- Nursing Workforce Grows, but Inequities Threaten Global Health GoalsGlobal nursing grows to 29.8M, but gaps persist, WHO warns shortages threaten UHC & health security goals.→
- One in two people facing cataract blindness need access to life-changing surgeryCataract surgery is one of the most powerful tools we have to restore vision and transform lives.→
- Operation sequence of bidirectional endoscopy with topical anesthesia affected colonoscopy performanceOptimizing Bidirectional Endoscopy: Study Examines How Procedure Sequence Impacts Quality & Performance!→
- Opioid-sparing multimodal analgesia for post-craniotomy painThis study aimed to compare the efficacy and safety of an opioid-sparing multimodal analgesia protocol versus a conventional opioid-based regimen for managing post-craniotomy pain.→
- Oral Semaglutide and Cardiovascular Outcomes in People With Type 2 Diabetes, According to SGLT2i UseThe SOUL trial found that oral semaglutide significantly reduced major adverse cardiovascular events in type 2 diabetes patients, regardless of concomitant SGLT2 inhibitor use. This suggests combining these treatments is both effective and safe for improving cardiovascular outcomes in this population.→
- Oral health status of outpatients with mental disorders in a specialist tertiary hospitalMental Health & Oral Health: Study Reveals Key Differences in Dental Health Among Psychiatric Patients!→
- Oral nutritional interventions in hospitalised older people at nutritional riskMalnutrition affects 35% to 64% of hospitalised older people, and is associated with adverse health outcomes such as disease complications and hospital readmission.→
- Oral nutritional supplementation in paediatric feeding difficultiesThis review highlights picky eating as a prevalent issue in children, exacerbating nutritional deficiencies, especially in low- to middle-income countries like South Africa.→
- Orthopaedic-related pathological conditions in the paediatric population presenting at outreach clinicsPaediatric orthopaedic outreach in central South Africa (1997-2016) revealed varied incidence rates of conditions like congenital talipes equinovarus and cerebral palsy across regions and age groups.→
- Overview and management of colds and fluSA flu deaths triple those in the US—HIV and TB burden heighten risk of severe illness. Know the difference.→
- Ozempic Important InformationOzempic Alert: SAHPRA Grants Exemption Amid Missing Side Effect Info—What You Need to Know!→
- Paediatric colistin prescribing practices in South Africa: A clinician surveyTo determine paediatric colistin prescribing practices and challenges in SA to aid the development of a paediatric colistin guideline.→
- Partners discuss improving pooled procurement of emergency medical countermeasuresThe WHO and the DG HERA brought together regional partners in Brussels for a workshop focused on pooled procurement of medical countermeasures – including diagnostics, treatments and vaccines – for health emergencies.→
- Patient safety can be improved with EHR-embedded medication decision supportFirst Databank’s tech integrates with electronic health records to guide clinicians on dosing and drug interactions, says SVP.→
- Patient-Facing Online Triage Tools and Clinician Decision-MakingOnline triage tools help manage primary care demand, guiding patients to calls, scripts, GP visits or referrals.→