Articles
662 entriesClinical reviews and commentary
- 'Exhalation' system improves symptoms for most common form of chronic sinus infectionsAn exhalation delivery system that uses a patient's own breath to carry the anti-inflammatory compound fluticasone (EDS-FLU) directly to the sinuses reduced chronic sinus infection (sinusitis) symptoms and decreased aggravations and infections associated with chronic inflammation of the sinus by more than 50 percent, researchers from the Perelman School of Medicine at the University of Pennsylvania reported.→
- 2025 saw fastest growth in IT spend since mid-'90sIn the healthcare space, that's probably because so many IT investments – not least in AI and machine learning – are starting to show ROI for hospitals and health systems.→
- 3 factors may lower depression risk, new evidence suggestsNew studies suggest lifestyle and treatment choices may reduce depression risk—GLP-1 meds like Ozempic, citrus fruits, and regular exercise all show promising protective effects.→
- A 1-week social media break could boost your mental healthCutting back on social media for a week resulted in less anxiety, depression, and insomnia for participants in a new study.→
- A 5-year retrospective study to determine the spectrum of crescentic glomerulonephritis in three tertiary hospitalsTo determine the causes of crescentic glomerulonephritis (CGN) in the South African (SA) setting.→
- A Spatiotemporal Analysis of Emergency Medical Services Use for Palliative Situations in Cape TownPalliative care unmet in LMICs, SA turns to EMS as a key partner to expand access and improve end-of-life care.→
- A cross-sectional study of patients with prosthetic mitral valves at a tertiary centre in Johannesburg, South AfricaThere is a high incidence of rheumatic valvular heart disease involving the mitral valve in Soweto, Johannesburg.→
- A rationale and framework for sharing mindfulness in trauma-dense communities in South AfricaMindfulness, stemming from ancient contemplative practices, cultivates present-moment awareness for well-being. Though modern interventions are widespread, their pedagogy has been largely Western. An exception, a Stellenbosch University programme, now provides a trauma-sensitive, Afro-centric curriculum, better suiting local needs and making mindfulness education more accessible.→
- A review on holistic and pharmacological management of insomniaStruggling to sleep? Discover the latest treatments for insomnia—from gold-standard CBT to new-gen sleep meds and more!→
- A roadmap for kidney health for South Africa in the context of universal health coverageChronic kidney disease (CKD) in South Africa (SA) is a growing public health crisis, driven by the intersecting burdens of HIV, tuberculosis, hypertension, diabetes and obesity.→
- A single dose of psilocybin may rewire the brain for lasting reliefMagic mushroom compound psilocybin may unlock powerful new relief for both pain and mood disorders.→
- A socio-ecological analysis of parents’ experiences of stillbirth in LimpopoStillbirth is a profoundly personal experience shaped by sociocultural norms, healthcare systems, and policies.→
- AI and public health – a major opportunityHospitals and health systems increasingly are adopting artificial intelligence technologies built into health IT such as EHRs, telehealth services, remote patient monitoring and other tools that can expand access to care and improve health equity.→
- AI could help identify abnormalities in unborn babies quickerAI-assisted pregnancy scans cut 20-week scan time by over 40%, nearly doubling speed and boosting patient care, study finds.→
- AI may aid in diagnosing adolescents with ADHDUsing artificial intelligence (AI) to analyze specialized brain MRI scans of adolescents with and without attention-deficit/hyperactivity disorder (ADHD), researchers found significant differences in nine brain white matter tracts in individuals with ADHD. Results of the study will be presented today at the annual meeting of the Radiological Society of North America (RSNA).→
- AI model may identify high-risk patients for post-transplant complicationsStem cell and bone marrow transplants are procedures that replace diseased, damaged, or destroyed blood-forming cells with healthy tissue.→
- AI tool could speed up coeliac diagnosisAn AI tool speeds up coeliac disease diagnosis, cuts waiting lists, and boosts pathologist efficiency, says new UK-led study.→
- AI-Based Pelvic Floor Surface Electromyography Reference Ranges and High-Precision Pelvic Floor Dysfunction DiagnosisThis study aims to improve pelvic floor sEMG diagnosis of PFDs using a new database for better reference ranges and AI.→
- AI-powered process improvement shows big patient experience ROI.UCHealth Yampa Valley hit 100% patient satisfaction by using automated workflows to improve surgical readiness and care experience.→
- About Motivation AssistanceMotivation Assistance provides assistance to HCPs to motivate for reimbursement of a medicine.→
- Accelerating the elimination of cervical cancerCervical cancer is the third most frequent cancer and the fourth cause of cancer death in females in Latin America and the Caribbean (LAC), despite it being highly preventable through HPV vaccination, screening and treatment.→
- Access to oncology care in western KwaZulu-Natal Province before, during and after the COVID-19 pandemicA South African study at Grey’s Hospital Oncology Department found that while patient waiting times for cancer care remained stable during COVID-19 lockdowns, the absolute number of new patients seen daily decreased. This was particularly true for referrals from primary care facilities, suggesting the pandemic's impact was more on initial diagnosis and referral pathways than on the tertiary hospital's capacity to treat patients who accessed care.→
- Adcock Ingram recalls Panado paediatric syrupUrgent Recall: Paracetamol Products Found with Quality Issues—Check Your Medicine for Safety Now!→
- Advancing wound care: Antiseptic strategies – povidone-iodineThis review examines the pharmacological properties of commonly used antiseptics in wound management.→
- Adverse childhood experiences, and violence and criminal justice outcomes in adulthoodGlobally, there is substantial evidence on the association between adverse childhood experiences (ACEs) and violence and criminal justice exposure.→
- Adverse health outcomes in offspring of parents with alcohol-related liver diseaseParental Alcohol Issues: Study Links ALD to Lifelong Health Risks in Offspring—Can Prevention Start at Home?→
- Aid cuts threaten fragile progress in ending maternal deaths, UN agencies warnMore women survive childbirth than ever, but UN warns progress is at risk as global aid cuts threaten maternal health gains.→
- Air travel and the risk of venous thromboembolismFlying raises your risk of blood clots—travellers should seek medical advice before long or frequent flights.→
- Alert to clinicians – Hantavirus Pulmonary SyndromeHantaviruses are zoonotic viruses associated with two clinical syndromes: Haemorrhagic Fever with Renal Syndrome (HFRS) and Hantavirus Pulmonary Syndrome (HPS; also called Hantavirus Cardiopulmonary Syndrome, HCPS).→
- Alert to clinicians – start of the 2026 Influenza and Respiratory Syncytial Virus (RSV) SeasonsRespiratory syncytial virus (RSV) is the leading cause of bronchiolitis and lower respiratory tract infections (LRTI) in young children and can lead to severe illness in infants.→
- Allostatic Load and Racial and Rural Disparities in Breast Cancer SurvivalDoes allostatic load help explain racial and rural disparities in breast cancer survival?→
- Almost one in ten children obese in first year of schoolChildhood Obesity on the Rise: Nearly 1 in 10 Kids Starting School Are Affected, New NHS Figures Reveal!→
- Alzheimer's is linked to low brain lithium levels, study showsA new study found that lithium naturally occurs in the brain and is crucial for normal function. A loss of lithium may be an early warning sign for Alzheimer’s disease as it binds to beta-amyloid plaques. In a mouse model, replenishing lithium levels reversed brain damage and restored memory function, offering a promising new avenue for both early detection and therapeutic intervention.→
- Ambient Documentation Technology in Clinician Experience of Documentation Burden and BurnoutIs the use of ambient documentation technology (ADT) associated with changes in clinician experience of documentation burden and burnout?→
- Amid a mental health crisis, technology can help psychiatrists focus on their specialtyDigital tools ease pressure on psychiatrists—telehealth now helps collect symptoms and guide patients.→
- An Overview of Respiratory Tract Infections in South AfricaThis review provides a comprehensive overview of respiratory tract infections in South Africa, detailing the classification, symptoms, and management of upper and lower respiratory diseases while highlighting the essential role of pharmacists in clinical assessment and vaccination.→
- An estimated 35 million new cancer cases to occur in 2050, WHO warnsWhile experts have made significant advances in treating cancer, cancer continues to remain a global health concern.→
- An open-label study on the safety and immunogenicity of a PD-1-enhanced DNA vaccine used as a T cell booster for COVID-19New COVID-19 DNA booster shows promise in elderly—tackles long-standing challenge of T cell response activation.→
- An overlooked connection: oral health status in patients with chronic diseasesOverlooked Connection: Study Reveals How Chronic Diseases Like Diabetes & Heart Disease Impact Oral Health!→
- An update on the Marburg Virus Disease outbreak in Ethiopia (January, 2026)The Ethiopian Ministry of Health (MoH) has declared an end to the country’s first confirmed Marburg Virus Disease (MVD) outbreak.→
- Anaemia in pregnancy: A survey of prevalence and associated factors in Vhembe DistrictAnaemia in pregnancy often reflects inadequate nutrition and is linked to adverse pregnancy outcomes.→
- Analysis of Health Systems Strengthening investment activities by Global Health InitiativesGlobal Health Initiatives (GHI) have played an important role in shaping health outcomes in countries through disease- and intervention-focused investments.→
- Analysis of factors affecting difficulty in handling oral medicine using electronic medication notebook-based personal health recordsA study using the harmo® electronic medication system found 24% of patients struggled to handle small tablets/capsules, particularly those with a combined length/width of ≤13.3 mm. Factors contributing to difficulty included impaired hand force, small formulation size, hypertension, and osteoporosis. These findings advocate for patient-centred oral medication design and prescribing practices to enhance adherence and safety.→
- Antifibrinolytics (lysine analogues) for the prevention of bleeding in people with haematological disordersPeople with haematological disorders are frequently at risk of severe or life‐threatening bleeding as a result of thrombocytopenia (reduced platelet count).→
- Antithrombotic Medications and Intraocular Hemorrhage Risk in Exudative Age-Related Macular DegenerationIs the use of anticoagulants or antiplatelets associated with intraocular haemorrhage in age-related macular degeneration?→
- Anxiety is linked to gut health: Could probiotics help treat it?Gut health linked to anxiety—reduced microbial diversity may worsen symptoms, while probiotics show potential benefits.→
- Artificial intelligence–driven kidney organ allocationKidney transplantation remains the optimal treatment for end-stage renal disease, yet persistent organ shortages and inequitable allocation necessitate innovative solutions.→
- Artificial neural networks date back to the 1950s – now they are ready to transform healthcareAI’s moment arrives—20 years in the making, new data convinces doctors to use it daily, Mayo expert says.→
- Assessment of adverse effects attributed to statin therapy in product labelsThis study evaluates the causal relationship between statin therapy and the adverse outcomes listed in current product labels.→
- Association of Statin Discontinuation in Pregnancy With Maternal Cardiovascular Health and Birth OutcomesPrevious cohort studies have focused mainly on statin foetal outcomes, with limited evidence about maternal cardiovascular health, particularly in high-risk women.→