Articles

662 entries

Clinical reviews and commentary

Implementing Active Surveillance for Tuberculosis: A Quality Improvement ProjectThis study evaluates how CHWs can implement active TB surveillance in South Africa, a country burdened by severe TB and MDR-TB epidemics.→
Improving Transparency in Clinical Trial ReportingCONSORT & SPIRIT 2025 launch—new guidelines aim to boost trial transparency, quality & impact.→
In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
In Case You Missed ItExplore a curated roundup of this week's articles, offering deep insights into the latest medical and healthcare advancements.→
In defence of South Africa’s National Health Research Ethics Council guidelines on heritable human genome editingHeart Failure Breakthrough? FINEARTS-HF Study Explores How Finerenone Impacts Different Ejection Fractions!→
In-ear microphones could help doctors 'listen' for early signs of Alzheimer'sCan Earbuds Detect Alzheimer’s Early? Scientists Explore Hearables for Diagnosing Neurodegenerative Diseases!→
Incidence of local anesthetic systemic toxicity in patients receiving bupivacaine infiltration analgesia for total joint arthroplasty under general anesthesiaHidden Risk in Surgery: Can Local Infiltration Analgesia Lead to Fatal Toxicity? New Research Explores the Danger!→
Incidence rates of hepatocellular carcinoma based on risk stratification in steatotic liver disease for precision medicine: A real-world longitudinal studySteatotic Liver Disease and Cancer: Study Targets Critical Gaps in Subgroup Incidence Rates to Guide Public Health Action!→
Incorporating Behavioral Science in Medication Adherence CommunicationSilent threat: Hypertension often goes untreated due to poor adherence—new strategies urgently needed.→
Increases in vaccine-preventable disease outbreaks threaten years of progress, warn WHO, UNICEF, GaviWHO & UNICEF sound alarm—vaccine-preventable diseases rise as immunization efforts face major setbacks.→
Infant Botulism Outbreak Linked to Infant FormulaInfant botulism happens when a baby swallows Clostridium botulinum spores that grow in the gut and make toxin.→
Infant formula poisonings: 36 cases reported in UK as experts issue advice to doctorsAt least 36 cases of babies becoming sickened from tainted infant formula supplies have been reported in the UK, officials say.→
Inflammatory diets, ultra-processed foods may increase Crohn's disease riskInflammatory bowel disease (IBD) is a group of chronic conditions that damage the intestines and can cause uncomfortable symptoms.→
Influences of Western Cape community service doctors’ choice regarding public, rural practiceDespite South Africa's compulsory community service aimed at boosting rural healthcare, few doctors intend to stay in these areas (8%). A Western Cape study found rural upbringing (6.5x more likely) and rural placements (7.7x/3.5x more likely) significantly influenced retention. Policies should prioritise rural background students and placements, alongside ensuring personal safety, job satisfaction, and mental health in rural facilities.→
Intermittent fasting may not aid weight loss, large review findsAdditional research into this area may be helpful to understand the full effects of intermittent fasting and how it may help people with certain conditions.→
Interruption in the Supply of Betamethasone Disodium Phosphate 4mg/ml InjectionWould you like a shorter version for email headers or an even more formal version for departmental memos?→
Intervention to Enhance Resilience Among Nurse Managers: A Systematic ReviewNurse managers are vital, high-stress healthcare links; COVID-19 amplified this, proving their resilience is critical for their well-being and team.→
Interventions for central serous chorioretinopathy: a network meta‐analysisA review of 67 RCTs on Central Serous Chorioretinopathy (CSC) found no single treatment definitively superior. While low-dose photodynamic therapy, supplements, and eplerenone showed potential for improving vision, the evidence is limited by small, poorly reported trials and low confidence in findings, highlighting a need for larger, high-quality research.→
Interventions for fertility preservation in women with cancer undergoing chemotherapyFor cancer patients undergoing chemotherapy, a review found that GnRH agonists may significantly reduce ovarian insufficiency in breast cancer, though other evidence is very uncertain. There's no clear evidence on live births or overall survival for either ovarian suppression or ovarian hyperstimulation with oocyte/embryo freezing, nor direct comparisons between the two.→
Intraoperative hypotension and postoperative risks in non-cardiac surgeryManaging Intraoperative Hypotension: Meta-Analysis Examines Best Strategies to Reduce Post-Surgery Complications!→
Investigating the role of knowledge management in the pharmaceutical sectorPoor knowledge management in pharma risks patient safety—linked to delays, errors, and poor outcomes.→
Iron deficiency anaemia: Managing symptoms and supporting self-careFighting Iron Deficiency: New Guide Equips Pharmacists to Lead the Charge in Managing Anaemia Worldwide!→
Is autism on the rise? Expert fact-checks recent claimsSocial media has boosted autism awareness, coinciding with an apparent rise in US diagnoses. This increase, however, isn't an "epidemic." Experts confirm it's due to broader diagnostic criteria, improved screening, and increased awareness, not primarily environmental factors, despite some claims.→
Is brain inflammation at the core of cognitive decline? What latest research saysNew research links brain inflammation and herpes viruses to dementia risk, while vaccines and anti-inflammatories may help prevent it.→
Is coffee good for your heart health? 3 studies offer insightsIs Your Coffee Helping or Harming Your Heart? Latest Research Unveils Caffeine’s Surprising Effects on Cardiovascular Health!→
Is excessive sleepiness as we age a warning sign of dementiaNew study links excessive sleepiness in women over 80 to double the risk of developing dementia within 5 years.→
Is your Patient’s Asthma Well-controlled?This review highlights the critical "perception gap" in asthma management, where many patients believe their condition is controlled despite failing to meet objective clinical criteria, and explores strategies like validated assessment tools and patient empowerment to achieve true control.→
Ischaemic Heart Disease: Pathophysiology, Diagnosis, and Therapeutic StrategiesIschaemic heart disease (IHD) remains the leading cause of global mortality, yet it is largely preventable through the targeted management of modifiable risk factors. This update explores contemporary diagnostic tools, therapeutic strategies, and the critical role pharmacists play in optimising patient outcomes.→
It’s time to talk to emergency medical dispatchersPerformance feedback and patient outcome follow-up are essential in emergency medical services.→
JAK inhibition decreases the autoimmune burden in Down syndromeImmune Dysregulation in Down Syndrome: Study Uncovers Key Mechanisms and Potential Therapeutic Targets!→
Join us at SAPHEX 2025!EMGuidance is Coming to SAPHEX 2025! Visit Stand C7 on 5-6 March at Sandton Convention Centre for Demos, Prizes & More!→
Just 1 hot dog per day could harm your health, study findsNew research in Nature Medicine links even small amounts of processed meat like hot dogs, sugary drinks, and trans fats to increased risks of cancer, type 2 diabetes, and heart disease. A daily hot dog, for instance, raised type 2 diabetes risk by 11%. While acknowledging the observational nature, experts urge minimising these foods and focusing on balanced, realistic dietary habits for improved health outcomes.→
Knowledge, attitudes and practices on hypertension among patients in a district hospitalA Tshwane study found that hypertension patients have positive attitudes but suboptimal knowledge and practices. Gaps included understanding blood pressure and risk factors. Higher education is linked to better knowledge/attitudes; age showed negative correlations. Targeted, socio-demographically tailored education is vital to improve adherence and management in South Africa.→
Korea pilots ambulance emergency platform built on 10 AI modelsSeverance Hospital researchers have developed an AI platform that converts paramedic voice reports into clinical records, predicts patient deterioration, and recommends suitable transfer hospitals.→
Lack of AI governance poses threat to data security, new HIMSS research showsAI Threats on the Rise: HIMSS25 Cybersecurity Forum to Tackle Next-Gen Healthcare Security Challenges!→
Leflunomide as an Alternative csDMARD for Rheumatoid Arthritis in a Resource-Constrained SettingRA treatment gaps in Africa, bDMARDs often unavailable despite poor prognosis; EULAR eyes LEF as a first-line option.→
Lipoprotein(a) as a Pharmacological Target: Premises, Promises, and ProspectsIs Lp(a) the Next Big Heart Risk? Emerging Research Reveals Its Powerful Role in Atherosclerosis & Cardiovascular Disease!→
Lived experiences of tuberculosis patients accessing treatment during COVID-19Despite being a preventable and curable disease, tuberculosis (TB) remains one of the deadliest infectious diseases, responsible for over a million deaths worldwide.→
Long-Term Scar Evolution and Ablation Lesion Assessment by Late Gadolinium Enhancement Cardiac Magnetic Resonance After Ventricular Tachycardia AblationThis study aimed to prospectively and systematically assess the long-term evolution of scar and ablation lesions using serial postablation LGE-CMR with long-term follow-up.→
Long-term cognitive effects of menopausal hormone therapyDoes Early Menopausal Hormone Therapy Boost Brain Health? 10-Year Study Revisits Cognitive Effects of Estradiol and Estrogens!→
Long-term efficacy and predictors of vagus nerve stimulation in drug-resistant epilepsyA number of indicators have been analysed for the relationship with the efficacy of vagus nerve stimulation (VNS) in drug-resistant epilepsy patients.→
Long-term yogurt consumption tied to decreased incidence of certain types of colorectal cancerCould Yogurt Help Prevent Colorectal Cancer? 30-Year Study Links Gut Bacteria to Lower Cancer Risk!→
Low sodium salt substitutes: a tool for sodium reduction and cardiovascular healthCochrane’s new systematic review on the efficacy and safety of low-sodium salt substitutes (LSSS), a tool for reducing salt intake in individuals and populations, is timely.→
Macrolides for the prevention of bronchopulmonary dysplasia in preterm neonatesBronchopulmonary dysplasia (BPD) continues to be the most frequent complication of extremely low‐birthweight neonates (< 1000 g) born before 28 weeks' gestational age (GA) (extremely premature neonates).→
Malaria Scorecard: Battles Have Been Won And Advances Made But The War Isn’t OverMalaria grips Africa, but progress is possible—collaboration is key to making limited resources count.→
Males born to obese mothers more likely to suffer health issues as adultsMales born to obese women are more likely to be overweight at birth and develop metabolic complications in later life, including liver disease and diabetes.→