Articles
52 entriesClinical reviews and commentary
- Macrolides for the prevention of bronchopulmonary dysplasia in preterm neonatesBronchopulmonary dysplasia (BPD) continues to be the most frequent complication of extremely low‐birthweight neonates (< 1000 g) born before 28 weeks' gestational age (GA) (extremely premature neonates).→
- Malaria Scorecard: Battles Have Been Won And Advances Made But The War Isn’t OverMalaria grips Africa, but progress is possible—collaboration is key to making limited resources count.→
- Males born to obese mothers more likely to suffer health issues as adultsMales born to obese women are more likely to be overweight at birth and develop metabolic complications in later life, including liver disease and diabetes.→
- Management of Erectile DysfunctionED affects men as young as 18—COVID-19 adds new risks. Learn about causes, classification, and treatment.→
- Many pregnancy-related complications going undetected and untreatedWHO Report: Severe Bleeding & Hypertension Leading Causes of Maternal Deaths—80,000 Lives Lost in 2020 Alone!→
- Marburg Outbreak in Ethiopia: Current SituationMarburg is a rare but severe viral haemorrhagic fever, similar to Ebola, that can cause serious illness and death.→
- Marburg Virus Disease (Frequently Asked Questions)Marburg virus disease (MVD), formerly known as Marburg haemorrhagic fever.→
- Mastering your fellowship: Part 1, 2026‘Mastering your Fellowship’ provides examples of the question formats encountered in the written and clinical examinations.→
- Mavacamten in Patients With Hypertrophic Cardiomyopathy Referred for Septal ReductionMavacamten, per the VALOR-HCM trial, significantly reduced the long-term need for septal reduction therapy in severely symptomatic obstructive hypertrophic cardiomyopathy patients.→
- Measles deaths down 88% since 2000, but cases surgeGlobal immunisation efforts have led to an 88% drop in measles deaths between 2000 and 2024, according to a new report from the WHO.→
- Measles: All you need to know!Measles is highly contagious—rash, fever, cough and more. In young, it can lead to blindness or death.→
- Measuring grass pollen allergens instead of grass pollen count will help hay fever sufferersMeasuring airborne grass allergen levels instead of pollen counts will be more beneficial for hay fever sufferers as new research shows grass allergen levels are more consistently associated with hay fever symptoms than grass pollen counts.→
- Mediation Effect of Body Mass Index on the Association Between Glycated Albumin and 10-year Atherosclerotic Cardiovascular Disease RiskCardiovascular diseases are global killers, and while HbA1c has been the go-to for glucose tracking, glycated albumin (GA) is the new, more reliable powerhouse set to revolutionize how we fight CVD.→
- Medical Product Alert N°1/2025: Falsified (contaminated) OXYCONTIN 80mgWHO Alert: Falsified OXYCONTIN 80mg Found in Unregulated Market—Counterfeit Opioid Poses Serious Health Risks!→
- Medical Product Alert N°1/2026: Substandard ACCUPAQUE (Iohexol), OMNIPAQUE (Iohexol) and VISIPAQUE (Iodixanol)This WHO Medical Product Alert refers to multiple batches of ACCUPAQUE, OMNIPAQUE and VISIPAQUE solutions for injection presented in 100 ml polypropylene containers.→
- Medical Product Alert N°3/2025: Falsified IMFINZI (durvalumab) Injection 500mg/10mlWHO warns of falsified IMFINZI in Iran & Türkiye—fake cancer drug poses serious health risks.→
- Medical Product Alert N°6/2025: Falsified SIMULECT (basiliximab) for injectionSIMULECT (basiliximab) is an immunosuppressant medicine classified as a monoclonal antibody.→
- Medical Product Alert N°7/2025: Falsified IBRANCE (palbociclib)Falsified IBRANCE (palbociclib) was identified in the WHO African, Eastern Mediterranean and European regions→
- Medical doctors employed in the South African state sector – unshielded on the frontline?A viral video by "Tom London" in September 2024 harshly criticised Helen Joseph Hospital doctors. While the Health Ombud substantiated infrastructure issues, claims of doctors' disrespect were unfounded. This incident highlights the vulnerability of South African public sector medical professionals to cyberbullying, given the lack of recourse against patient aggression.→
- Medicines Syringe Compatibility CheckerThis Medicines Compatibility Checker is a practical guide for mixing medicines for I.V administration.→
- Mediterranean diet may not improve brain health in all aging populationsA new study suggests the Mediterranean diet intervention did not improve cognitive function in African Americans, contrary to previous findings. While participants showed clinically meaningful weight loss and enhanced dietary adherence, no cognitive benefits were observed within 14 months. Researchers believe longer-term interventions are needed to assess potential cognitive improvements in this demographic.→
- Meet the Team at SAPHEX 2025Meet the EMGuidance Team at SAPHEX 2025! Join Us on 5-6 March at Sandton Convention Centre for Insights & Innovation!→
- Men undergoing medical circumcision at a community health centre: Knowledge and attitudesThis study explored men’s knowledge and attitudes toward medical male circumcision (MMC) and its role in reducing HIV transmission.→
- Meningococcal Disease in the Democratic Republic of the CongoThere is an outbreak of meningococcal disease in the Mangembo Health Zone of Kongo Central Province.→
- Menopausal hormone therapy and central nervous system tumors: Danish nested case-control studyMeningiomas are the most common benign tumors of the central nervous system (CNS) and occur more frequently in women, with a female:male ratio of up to 3.5, the greatest ratio being among middle-aged individuals.→
- Mental health update – update on depression with a focus on vortioxetineFighting Depression in Africa: Can Vortioxetine’s Unique Mechanism Offer New Hope for Millions?→
- Metabolic Health and Heterogenous Outcomes of Prenatal InterventionsDo preexisting metabolic phenotypes of obesity differentially influence the outcomes of a prenatal lifestyle intervention aimed at reducing excess gestational weight gain?→
- Minimising the usage of desflurane only by education and removal of the vaporisers – a before-and-after-trialCan Green Healthcare Start in the OR? Study Shows Simple Steps to Cut Desflurane Use & Reduce Emissions!→
- Mitochondrial-Mediated Platelet Activation in Polymyalgia RheumaticaCould Mitochondria Hold the Key to Polymyalgia Rheumatica? Study Explores Their Role in Platelet Activation & Disease Pathogenesis!→
- Mobile vans helping people in coastal areas to be part of researchMobile research units in England aim to boost clinical trial access by bringing studies directly to coastal communities.→
- Modifiable Parental Factors and Adolescent Sleep During Early AdolescenceHow are modifiable parental factors when children are 9 to 11 years of age associated with adolescent sleep at 13 to 14 years of age?→
- Molecular assays for the diagnosis of sepsis in neonates: a diagnostic test accuracy reviewTraditional microbial cultures for diagnosing neonatal sepsis have low sensitivity and are slow, but rapid molecular assays offer promising advances that could improve outcomes in newborns.→
- More countries report rising levels of drug-resistant gonorrhoea, warns WHOThe WHO warns that gonorrhoea, a sexually transmitted infection, is becoming increasingly resistant to antibiotics, according to new data.→
- Mortality Trends and Causes of Death in a South African Hospital Complex Pre- and During COVID-19COVID-19 dramatically reversed South Africa's declining mortality trend, significantly increasing all-cause deaths from April 2020 to March 2022.→
- Mortality rate in patients in a long-term psychiatric care facility in Johannesburg.Severe Mental Illness Cuts Lifespan by 15-20 Years—Addressing the Alarming Mortality Gap in Mental Health Care!→
- Multi-kingdom gut microbiota dysbiosis is associated with the development of pulmonary arterial hypertension.Emerging research reveals gut microbiota imbalances may drive idiopathic pulmonary arterial hypertension via the gut–lung axis.→
- Multimorbidity phenotypes and associated characteristics in severe asthmaThe phenotypic nature of multimorbidity in severe asthma is poorly understood. This study aims to define multimorbidity phenotypes and their characteristics in severe asthma across Europe by identifying and characterising co-aggregation of comorbidities.→
- Muscle loss from GLP-1 drugs may not be as high as thought.While past studies show that adults taking a GLP-1 medication can lose between 5-15% of their starting body weight, other research reports that a good portion of that weight loss comes from muscle loss.→
- Musculoskeletal painMusculoskeletal pain affects nearly half the population, impacting all ages and causing emotional stress, physical decline, and disability. It should be treated as a distinct condition, not solely a symptom.→
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