Guidelines
180 entriesNDOH Standard Treatment Guidelines and clinical protocols
- Management of Incomplete Miscarriage in the 1st Trimester, at Primary Health Care LevelGeneral measures Medicine treatment Referral O02.1/O03.4 Both Manual Vacuum Aspiration (MVA) and medical evacuation are equally effective for miscarriage. GENERAL MEASURES Counselling. Evacuation of the uterus. MEDICINE TREATMENT Medical evacuation: Misoprostol, SL/PV/buccal, 800 mcg immediately as a single dose. Repeat after 24 hours if necessary. LoE:IIIb 1 Manual vacuum aspirPrimary Care→
- Management of Indeterminate PCR Results in Infants.Click on the image to enlarge. # Final HIV status cannot be determined until the infant has stopped all antiretroviral prophylaxis and is at least 6 weeks post-cessation of breastfeeding. In cases where clients have been initiated on ART and diagnosis remains uncertain, clients should be referred for further management by a specialist clinical and laboratory team. ART should never be stopped withOther→
- Management of Menopausal SymptomsNEW Management of Menopausal Symptoms (compiled from the EDL and NICE 2015)Other→
- Management of Paediatric Cases of Alleged Sexual Assault - Rapid ApproachManagement of paediatric cases of alleged sexual assaultOther→
- Management of PainManagement of painPEML (Paeds)→
- Management of Pressure Sores in Surgical WardsGuidelines for the Management of Pressure Sores in Surgical WardsOther→
- Management of Procedural PainGeneral principles and management of cancer pain in adultsOther→
- Management of RR-TB Among People Living with HIVKey Principles Considerations RR-TB/HIV co-infected clients Antiretroviral Therapy in HIV-infected persons with RR-TB Earlier antiretroviral agents that are no longer recommended in standard care Assessment of renal function before starting tenofovir The content of this chapter is aligned with the National 2023 ART Clinical Guideline [16] . Key Principles The short and longer DR-TB regimens may bOther→
- Management of RR-TB and Other Co-MorbiditiesThis section has been included in this clinical guidance because it is essential. However, there is no update here. The information is based on existing clinical reference guide [11] . Co-morbid condition Management strategies Diabetes mellitus - Excellent glucose control (may need insulin). - Close monitoring of blood glucose and HbA1C. - Close monitoring for adverse events that may beOther→
- Management of RR-TB in Children Above 15 Years of Age and Non-Pregnant AdultsKey points regarding the Short Regimen for RR-TB (BPaL-L) Initial approach to patients diagnosed with RR-TB Inclusion and exclusion criteria for Short RR-TB Regimen Switching from BPaL-L to long individualized regimen Longer Individualized Regimens for RR-TB: Summary Points WHO Drug Groupings Recommended dosing of drugs for RR-TB treatment in persons weighing ≥30 kg Key points regarding the ShortOther→
- Management of RR-TB in Children Under 15 Years of AgeIntroductory remarks Principles of RR-TB treatment in children under 15 years of age Approach to treatment of RR-TB in children under 15 years of age Sample individualized regimens for children under the age of 15 years ART regimen modification for children aged one month to <10 years, and >3 to <30 kg, living with HIV and on ART at RR-TB treatment initiation Weight-based dosing recommenOther→
- Management of Selected Antiretroviral Adverse Drug ReactionsPlease click on the link below to access the most up-to-date version of this guideline. The content on this page is currently being updated to align with the latest publication. Always check the version number at the bottom of the screen to confirm which version you are using. Click here to access the Adult Hospital Level Chapter 10: HIV_and_AIDS_with_supporting_NEMLC_Report_Reviews_2025-9-VersioEML (Adult)→
- Management of Shocked ChildManagement of a shocked childOther→
- Management of Status EpilepticusPaediatrics - Management of Status EpilepticusOther→
- Management of Suspected Choking/ Foreign Body Aspiration in ChildrenICD-10 code: T17.2-5/T17.8-9/ T18.0-1 Table 21.3: Managing suspected choking/foreign body aspiration in children If the child is able to talk and breathe Encourage the child to cough repeatedly while arranging transfer urgently with supervision. If the child is conscious but with no effective cough or breathing Give up to 5 abdominal thrusts and if ineffective up to 5 back slaps, followed by re-aPrimary Care→
- Management of Termination of Pregnancy at Primary Health Care Level: Gestation up to 12 Weeks and 0 DaysGeneral measures Medicine treatment Referral O04.9 GENERAL MEASURES Confirm pregnancy with urine pregnancy test. Determine gestational age with ultrasound. If ultrasound is unavailable, use dates (LMP) and bimanual (pelvic) examination. If unsure of dates, or examination disagrees with dates, or uterus palpable abdominally, or the woman is obese or difficult to examine, arrange pre-procedure ultrPrimary Care→
- Management of Woman at High Risk for Recurrent Second Trimester Miscarriage or Preterm Birth in Singleton Pregnancies (Risk for PTL)These protocols are intended for the use of students, interns and registrars within Tygerberg hospital and its immediate catchment area only. Always consult with a senior colleague if you are unsure of the correct management.Other→
- Management of a High Maternal Viral Load after DeliveryClick on image to enlarge Click here for the ART Initiation Algorithm . Click here for the VL Monitoring schedule . Click here for the VL Non-Suppression Algorithm . Click here for the Dosing Charts for Prophylaxis for the HIV-Exposed Infant . Click here for the Stopping Breastfeeding . Click here for the pdf . South African National Department of Health, Guideline for VeOther→
- Management of cervical cytology smears in Tygerberg Hospital GSAAbbreviations Who must get cervical screening Signs and symptoms of cervical cancer What to look our for when doing a cervical smear What should women do to prevent abnormal cervical smears Interpretation of cervical smear What to tell the patient about the reason for referral to colposcopy HPV testing What to do with HPV results Follow up after LLETZ Follow up after hysterectomy for CIN lesionsOther→
- Management of the Asphyxiated NewbornNational Neonatal Resuscitation GuidelinesOther→
- Management of the Brain Dead Potential DonorManagement of the brain dead potential donorOther→
- Management of the Hepatitis B Exposed InfantClick on the image to enlarge. Note: Providers should wait until the infant is 9 months of age, and at least one to two months after the last dose of HBV vaccine to perform the Post Vaccination Serologic Tests (PVST). Tests performed before 9 months of age can provide inaccurate anti-HBs results by detecting passive antibodies from HBIG/HBV vaccine administered at birth rather than actual responsOther→
- Management of the Infant of a Mother with TBManagement guidelines for students, interns and registrars on a variety of routine and emergency situations in our neonatal service at Tygerberg Children’s Hospital. Published in 2014.Other→
- Management of the Newborn Exposed to TBClick on the image to enlarge. Click here for the Annexure 5 TPT Dosing Tables . Click here for the pdf . South African National Department of Health, Guideline for Vertical Transmission Prevention of Communicable Infections, Version 2_August 2023Other→
- Managing COVID-19 Cases in SchoolsPublished 23 May 2020Other→
- Managing Diabetic Patients in Surgical WardsManaging Diabetic Patients in Surgical WardsOther→
- Manual Vacuum Aspiration (MVA)This booklet is intended as a practical guide to patient care for registrars, medical officers, interns and medical students attached to the gynaecology units at the University of the Witwatersrand Academic Hospitals. Anyone can use it.Other→
- Marsupialisation of Bartholin's AbscessThis booklet is intended as a practical guide to patient care for registrars, medical officers, interns and medical students attached to the gynaecology units at the University of the Witwatersrand Academic Hospitals. Anyone can use it.Other→
- Massive Haemorrhage With Massive Transfusion of BloodDefinition Diagnostic Criteria Medicine Treatment Referral DEFINITION Massive blood loss in children is recognised when a child requires a blood transfusion to replace 50% of total blood volume in 3–4 hours (40 mL/kg) or > 100% of total blood volume in 24 hours or receives replacement of 10% of total blood volume/minute. The rapid recognition is important to maintain tissue oxygenation by restPEML (Paeds)→
- Massive Transfusion Guidelines• More than 10 units in 24 hours • Replacement of entire blood volume in 24 hours • Replacement of more than 50% of total blood volume within 3 hours • Rate of loss >150ml/min.Other→
- Massive Transfusion Guidelines (Adult)Massive Transfusion GuidelinesOther→
- Massive Transfusion Guidelines: SummaryMassive transfusionOther→
- Massive Transfusion Guidelines: Summary (Adult)Summary of the Massive Transfusion Guidelines for AdultsOther→
- Massive Transfusion ProtocolDescription Major haemorrhage may be defined as blood loss >150 ml/min, loss of >50% of blood volume in 3 hours, or loss of entire blood volume in 24 hours. A massive transfusion may also be defined by the transfusion of >4 units of red blood cells in 1 hour, replacement of >50% of blood volume in 3 hours (>5 units in 3 hours), or the replacement of entire blood volume in 24 hoursEML (Adult)→
- MastitisDescription General measures Medicine treatment Referral O91.2 DESCRIPTION Inflammation of the breast tissue surrounding the milk ducts. Risk factor includes retrograde infection from a fissured nipple and milk stasis. Commonly isolated pathogens include S. aureus and S. epidermidis. Presentation includes painful breast(s), fever, erythema and malaise. GENERAL MEASURES Compresses. Regular expressPrimary Care→
- MastoiditisInfection Mastoiditis Brief outline/clinical setting Infection of the temporal bone (mastoid), is typically a complication of acute otitis media. Distinction must be made between clinical and radiographic mastoiditis. Clinical disease presents with otalgia, headache, fever and results in Post auricular skin changes, Mastoid tenderness, Auricular protrusion, Fullness of the posterior superior EACOther→
- MastoiditisStandard Treatment Guidelines and Essential Medicines List for South Africa, Hospital Level, Adults 2019 EditionEML (Adult)→
- Maternal DeathsThe guidelines recommend management of common obstetric conditions at primary and referral level, based on local experience and evidence-based practice. They are not intended as strict protocols nor as standard operating procedures, but rather as a guide to safe effective management of common obstetric problems. The guidelines should be most useful to interns, medical officers and registrars.Other→
- Maternal Mental HealthIn vulnerable women, pregnancy exacerbates the risk of developing a mental illness. Approximately one in three women in South Africa have depression and/or anxiety in the perinatal period. Globally, postpartum psychosis affects 1 to 2 women in every 1000 after childbirth. Risk factors for maternal mental illness include past history of mental illness, recent major life event, (e.g. bereavement) ePrimary Care→
- Maternal ResuscitationMaternal ResuscitationOther→
- MeaslesCase Definition Description General Measures Medicine Treatment Referral ICD-10 codes: B05.0-4/B05.8-9 Note: Notifiable medical condition CASE DEFINITION Fever. AND Red maculopapular (blotchy) rash. AND Cough or coryza (runny nose) or conjunctivitis. Inform the local EPI co-ordinator about all cases of suspected measles, (i.e. which fulfil the case definition criteria). Send clotted blPrimary Care→
- MeaslesMeaslesOther→
- MeaslesGuideline to the management of measles in the paediatric patientOther→
- MeaslesDescription Diagnostic criteria General and supportive measures Medicine treatment Referral ICD-10 code: B05 *Notifiable condition DESCRIPTION The following case definition is an epidemiological and not a diagnostic tool: Fever and maculopapular rash with any one of the following: cough, coryza/runny nose, conjunctivitis. Suspect measles in any child fulfilling the case definition. An acutePEML (Paeds)→
- Measles (Age 2 months up to 5 years)IMCI - Child (Age 2 months up to 5 years)IMCI→
- Measles - Follow-UpIMCI - Child (Age 2 months up to 5 years)IMCI→
- Measurement of Renal Function by Assessment of GFRMeasurement of GFR using exogenous markers may be required in special situations such as when dosing toxic drugs with a narrow therapeutic window, and in the assessment of living renal donors prior to kidney donation. Radioisotope markers such as 99m Tc-DTPA are commonly used. In practice, the usual way of assessing renal function is by estimating GFR from serum creatinine using a prediction equaOther→
- Measuring ImprovementSupporting the Antimicrobial Resistance Strategy Framework and the Guidelines on Implementation of the Antimicrobial Strategy in South Africa: One Health Approach and Governance, 2018Other→
- Medical EmergenciesStandard Treatment Guidelines and Essential Medicines List for South Africa, Hospital Level, Adults 2019 EditionEML (Adult)→
- Medical Management of Ectopic PregnancyGeneral measures Medicine treatment Referral ICD-10 code: O00.0-2/O00.8-9 GENERAL MEASURES Ruptured or suspected rupture of an ectopic pregnancy should be managed with urgent resuscitation and surgery. There must be certainty that there is no viable intra-uterine pregnancy. The discriminatory zone is the β-hCG level above which an ultrasound is likely to visualise a gestational sac within tEML (Adult)→